Evidence map›Paper›PMID 37221438›Full record

ReviewWorld journal of microbiology & biotechnology2023

Clinical manifestations and immune response to tuberculosis.

Mary Lilián Carabalí-Isajar, Oscar Hernán Rodríguez-Bejarano, Tatiana Amado, Manuel Alfonso Patarroyo, María Alejandra Izquierdo, Juan Ricardo Lutz, Marisol Ocampo

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Extrapulmonary tuberculosis in Morocco: A systematic review of observational studies.Revista da Sociedade Brasileira de Medicina Tropical · 2025
    Pooled it
  2. Review
  3. Article
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  6. Article
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  10. Article
  11. Article
  12. Review
  13. Article
  14. Host- and pathogen-related determinants of pulmonaryEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Drug resistance mechanisms inFrontiers in pharmacology · 2026
    Review
  20. LncRNAAnnals of medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Mary Lilián Carabalí-IsajarFundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50#26-20, 111321, Bogotá, Colombia.
Oscar Hernán Rodríguez-BejaranoHealth Sciences Faculty, Universidad de Ciencias Aplicadas y Ambientales (UDCA), Calle 222#55-37, 111166, Bogotá, Colombia.
Tatiana AmadoFundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50#26-20, 111321, Bogotá, Colombia.
Manuel Alfonso PatarroyoFundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50#26-20, 111321, Bogotá, Colombia.
María Alejandra IzquierdoMedicine Department, Hospital Universitario Mayor Mederi, Calle 24 # 29-45, 111411, Bogotá, Colombia.
Juan Ricardo LutzMedicine Department, Hospital Universitario Mayor Mederi, Calle 24 # 29-45, 111411, Bogotá, Colombia. juan.lutz@mederi.com.co.
Marisol OcampoFundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50#26-20, 111321, Bogotá, Colombia. mocampoc@udistrital.edu.co.
Fundación Instituto de Inmunología de Colombia · COHospital Universitario Mayor, MederiHospital Universitario San Ignacio · COUniversidad Distrital Francisco José de Caldas · COUniversidad Nacional de Colombia · COUniversity of Applied and Environmental Sciences · CO

Funding

Faculty of Medicine, Universidad Nacional de Colombia, Carrera 45#26-85, Bogotá 111321, Colombia dFundación Instituto de Inmunología de Colombia (FIDIC), Carrera 50#26-20, Bogotá 111321, Colombia aHealth Sciences Faculty, Universidad de Ciencias Aplicadas y Ambientales (UDCA), Calle 222#55-37, Bogotá 111166, Colombia cMedicine Department, Hospital Universitario Mayor Mederi, Calle 24 # 29-45, Bogotá 111411. Colombia ePhD Program in Biomedical and Biological Sciences, Universidad del Rosario, Carrera 24#63C-69, Bogotá 111221, Colombia bUniversidad Distrital Francisco José de Caldas, Carrera 3#26A-40, Bogotá 110311, Colombia f
6 · The paper itself

Abstract

Tuberculosis is a far-reaching, high-impact disease. It is among the top ten causes of death worldwide caused by a single infectious agent; 1.6 million tuberculosis-related deaths were reported in 2021 and it has been estimated that a third of the world's population are carriers of the tuberculosis bacillus but do not develop active disease. Several authors have attributed this to hosts' differential immune response in which cellular and humoral components are involved, along with cytokines and chemokines. Ascertaining the relationship between TB development's clinical manifestations and an immune response should increase understanding of tuberculosis pathophysiological and immunological mechanisms and correlating such material with protection against Mycobacterium tuberculosis. Tuberculosis continues to be a major public health problem globally. Mortality rates have not decreased significantly; rather, they are increasing. This review has thus been aimed at deepening knowledge regarding tuberculosis by examining published material related to an immune response against Mycobacterium tuberculosis, mycobacterial evasion mechanisms regarding such response and the relationship between pulmonary and extrapulmonary clinical manifestations induced by this bacterium which are related to inflammation associated with tuberculosis dissemination through different routes.

Indexed as

Mycobacterium tuberculosisTuberculosisCytokinesHumansInflammationPublic HealthCytokinesClinical manifestationsImmune responseMycobacterium tuberculosisTuberculosis

Identifiers

PMID37221438
PMCPMC10205569
OpenAlexW4377940992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.