Evidence map›Paper›PMID 37221355›Full record

ArticleCancer causes & control : CCC2023

Diabetes risk reduction diet and ovarian cancer risk: an Italian case-control study.

Giovanna Esposito, Federica Turati, Fabio Parazzini, Livia S A Augustin, Diego Serraino, Eva Negri, Carlo La Vecchia

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Association between diet quality and ovarian cancer risk and survival.Journal of the National Cancer Institute · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Giovanna EspositoDepartment of Clinical Sciences and Community Health, University of Milan, Via Giovanni Celoria 22, Milan, 20133, Italy. giovanna.esposito@unimi.it.ORCID http://orcid.org/0000-0001-7894-4456
Federica TuratiDepartment of Clinical Sciences and Community Health, University of Milan, Via Giovanni Celoria 22, Milan, 20133, Italy.
Fabio ParazziniDepartment of Clinical Sciences and Community Health, University of Milan, Via Giovanni Celoria 22, Milan, 20133, Italy.
Livia S A AugustinEpidemiology and Biostatistics Unit, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Naples, Italy.
Diego SerrainoUnit of Cancer Epidemiology, Centro di Riferimento Oncologico (CRO), IRCCS, Aviano, Italy.
Eva NegriDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Carlo La VecchiaDepartment of Clinical Sciences and Community Health, University of Milan, Via Giovanni Celoria 22, Milan, 20133, Italy.
University of Milan · ITCentro di Riferimento Oncologico · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the relation between a diabetes risk reduction diet (DRRD) and ovarian cancer.

methodsWe used data from a multicentric case-control study conducted in Italy, including 1031 incident ovarian cancer cases and 2411 controls admitted to hospital centres for acute non-malignant disease. Subjects' diet prior to hospital admission was collected using a validated food frequency questionnaire. Adherence to the DRRD was measured using a score based on 8 dietary components, giving higher scores for greater intakes of cereal fiber, coffee, fruit, nuts, higher polyunsaturated to saturated fatty acids ratio, lower glycemic index of diet, and lower intakes of red/processed meat, and sweetened beverages/and fruit juices. Higher scores indicated greater adherence to the DRRD. Multiple logistic regression models were fitted to calculate the odds ratios (OR) of ovarian cancer and the corresponding 95% confidence intervals (CI) for approximate quartiles of the DRRD score.

resultsThe DRRD score was inversely related to ovarian cancer, with an OR of 0.76 (95%CI: 0.60-0.95) for the highest versus the lowest quartile of the score (p for trend = 0.022). The exclusion of women with diabetes did not change the results (OR = 0.75, 95%CI: 0.59-0.95). Inverse associations were observed in strata of age, education, parity, menopausal status, and family history of ovarian/breast cancer.

conclusionHigher adherence to a diet aimed at reducing the risk of diabetes was inversely associated with ovarian cancer. Further evidence from prospective investigations will be useful to support our findings.

Indexed as

Diabetes MellitusOvarian NeoplasmsCase-Control StudiesDietEye Diseases, HereditaryFemaleHumansProspective StudiesRetinal DetachmentRisk FactorsRisk Reduction BehaviorCase-control studyDiabetesDietGlycemic indexOvarian cancer

Identifiers

PMID37221355
PMCPMC10363049
OpenAlexW4377862033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.