ArticleScientific reports2023
Temporal evolution of mechanical stimuli from vascular remodeling in response to the severity and duration of aortic coarctation in a preclinical model.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Severity and duration-dependent aortic stiffening in a rabbit coarctation model identifies constitutive material parameters as promising regional biomarkers for hypertension progression.Scientific reports · 2026Article
- Resistant Secondary Hypertension and Severe Pulmonary Hypertension in a Young Adult due to a Rare Cause.Clinical case reports · 2025Article
- Establishing Hemodynamic Convergence Framework for Coronary Digital Twins Under Realistic Dynamic Heart Rates.Physics of fluids (Woodbury, N.Y. : 1994) · 2025Article
- A Novel Diastolic Doppler Index Less Affected by Aortic Arch Anomalies Co-existing with Coarctation.Pediatric cardiology · 2025Article
- Computational model of coarctation of the aorta in rabbits suggests persistent ascending aortic remodeling post-correction.Biomechanics and modeling in mechanobiology · 2025Article
- Coarctation Duration and Severity Predict Risk of Hypertension Precursors in a Preclinical Model and Hypertensive Status Among Patients.Hypertension (Dallas, Tex. : 1979) · 2024Article
- A Systems Approach to Biomechanics, Mechanobiology, and Biotransport.Journal of biomechanical engineering · 2024Article
- Coarctation duration and severity predict risk of hypertension precursors in a preclinical model and hypertensive status among patients.medRxiv : the preprint server for health sciences · 2024Article
- Consistency of the continuous flow pressure gradient despite aortic arch anomalies co-existing with coarctation.medRxiv : the preprint server for health sciences · 2023Article
- Modeling Dynamics of the Cardiovascular System Using Fluid-Structure Interaction Methods.Biology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Coarctation of the aorta (CoA) is one of the most common congenital cardiovascular diseases. CoA patients frequently undergo surgical repair, but hypertension (HTN) is still common. The current treatment guideline has revealed irreversible changes in structure and function, yet revised severity guidelines have not been proposed. Our objective was to quantify temporal alterations in mechanical stimuli and changes in arterial geometry in response to the range of CoA severities and durations (i.e. age of treatment) seen clinically. Rabbits were exposed to CoA resulting in peak-to-peak blood pressure gradient (BPG
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Registered trials
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