ArticleNature communications2023
Goal-oriented representations in the human hippocampus during planning and navigation.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Action information is integrated into entorhinal representations of conceptual space and is reflected in eye movements.PLoS biology · 2026Article
- Eye movements reflect memory-related theta activity in the human brain.PLoS biology · 2026Article
- Differential representations of spatial environments in mPFC and hippocampus underpinning flexible navigation.NeuroImage · 2026Article
- Neural sampling from cognitive maps enables goal-directed imagination and planning.Nature machine intelligence · 2026Article
- Complementary roles of dorsal and ventral hippocampus in the flexible adaptation of goal-directed behavior.Science advances · 2025Article
- Factorized embedding of goal and uncertainty in the lateral prefrontal cortex guides stably flexible learning.Nature communications · 2025Article
- The Primate Hippocampus Constructs a Temporal Scaffold Anchored to Behavioral Events.bioRxiv : the preprint server for biology · 2025Article
- Disentangling structure-function relationships between the human hippocampus and the whole brain using track-weighted dynamic functional connectivity.bioRxiv : the preprint server for biology · 2025Article
- Micro-variations in timing and loudness affect music-evoked mental imagery.Scientific reports · 2025Article
- Empowering safer socially sensitive autonomous vehicles using human-plausible cognitive encoding.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Neural codes track prior events in a narrative and predict subsequent memory for details.Communications psychology · 2025Article
- Memory-based predictions prime perceptual judgments across head turns in immersive, real-world scenes.Current biology : CB · 2025Article
- Real-world goal-directed behavior reveals aberrant functional brain connectivity in children with ADHD.PloS one · 2025Article
- Differences and similarities between human hippocampal low-frequency oscillations during navigation and mental simulation.bioRxiv : the preprint server for biology · 2024Article
- Context changes retrieval of prospective outcomes during decision deliberation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- The brain hierarchically represents the past and future during multistep anticipation.Nature communications · 2024Article
- The brain hierarchically represents the past and future during multistep anticipation.bioRxiv : the preprint server for biology · 2024Article
- A spatial transformation-based CAN model for information integration within grid cell modules.Cognitive neurodynamics · 2024Article
- Forming cognitive maps for abstract spaces: the roles of the human hippocampus and orbitofrontal cortex.Communications biology · 2024Article
- An experimental framework for conjoint measures of olfaction, navigation, and motion as pre-clinical biomarkers of Alzheimer's disease.Journal of Alzheimer's disease reports · 2024Review
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6 authors.
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Abstract
Recent work in cognitive and systems neuroscience has suggested that the hippocampus might support planning, imagination, and navigation by forming cognitive maps that capture the abstract structure of physical spaces, tasks, and situations. Navigation involves disambiguating similar contexts, and the planning and execution of a sequence of decisions to reach a goal. Here, we examine hippocampal activity patterns in humans during a goal-directed navigation task to investigate how contextual and goal information are incorporated in the construction and execution of navigational plans. During planning, hippocampal pattern similarity is enhanced across routes that share a context and a goal. During navigation, we observe prospective activation in the hippocampus that reflects the retrieval of pattern information related to a key-decision point. These results suggest that, rather than simply representing overlapping associations or state transitions, hippocampal activity patterns are shaped by context and goals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.