Evidence map›Paper›PMID 37221160›Full record

ArticleNature communications2023

Cultured meat platform developed through the structuring of edible microcarrier-derived microtissues with oleogel-based fat substitute.

Feng-Chun Yen, Jovana Glusac, Shira Levi, Anton Zernov, Limor Baruch, Maya Davidovich-Pinhas, Ayelet Fishman, Marcelle Machluf

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Integrative Adipogenic Engineering of Cultured Fat for Cell Based Meat.Comprehensive reviews in food science and food safety · 2026
    Review
  8. Edible Scaffolds for Cultivated Meat Production.Advances in biochemical engineering/biotechnology · 2026
    Review
  9. Review
  10. Could Cultured Meat Be a Sustainable and Safe Source of Protein?Molecular nutrition & food research · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Scaling Cultured Meat: Challenges and Solutions for Affordable Mass Production.Comprehensive reviews in food science and food safety · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Feng-Chun Yen *Faculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel.ORCID 0009-0009-4514-1003
Jovana Glusac *Faculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel.ORCID 0000-0001-8335-2025
Shira LeviFaculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel.
Anton ZernovFaculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel.
Limor BaruchFaculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel.
Maya Davidovich-PinhasFaculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel. dmaya@bfe.technion.ac.il.ORCID 0000-0002-0268-9943
Ayelet FishmanFaculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel. afishman@technion.ac.il.ORCID 0000-0002-1644-9377
Marcelle MachlufFaculty of Biotechnology & Food Engineering, Technion - Israel Institute of Technology, 3200003, Haifa, Israel. machlufm@bfe.technion.ac.il.ORCID 0000-0001-5896-963X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing global demand for meat, cultured meat technologies are emerging, offering more sustainable solutions that aim to evade a future shortage of meat. Here, we demonstrate a cultured meat platform composed of edible microcarriers and an oleogel-based fat substitute. Scalable expansion of bovine mesenchymal stem cells on edible chitosan-collagen microcarriers is optimized to generate cellularized microtissues. In parallel, an oleogel system incorporated with plant protein is developed as a fat substitute, which is comparable to beef fat in appearance and texture. Combining the cellularized microtissues with the developed fat substitute, two types of cultured meat prototypes are introduced: layered cultured meat and burger-like cultured meat. While the layered prototype benefits enhanced stiffness, the burger-like prototype has a marbling meat-like appearance and a softer texture. Overall, this platform and the established technological basis may contribute to the development of different cultured meat products and promote their commercial production.

Indexed as

ChitosanFat SubstitutesMeat ProductsAnimalsCattleMeatOrganic ChemicalsChitosanFat SubstitutesoleogelsOrganic Chemicals

Identifiers

PMID37221160
PMCPMC10205709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.