Evidence map›Paper›PMID 37220621›Full record

ArticleJournal of Alzheimer's disease reports2023

Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of

Sandra den Hoedt, Kristien Y Dorst-Lagerwerf, Helga E de Vries, Annemieke J M Rozemuller, Philip Scheltens, Jochen Walter, Eric J G Sijbrands, Pilar Martinez-Martinez, Adrie J M Verhoeven, Charlotte E Teunissen and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of Alzheimer's disease reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Sandra den HoedtDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Kristien Y Dorst-LagerwerfDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Helga E de VriesDepartment of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Amsterdam University Medical Center, Free University Amsterdam, The Netherlands.
Annemieke J M RozemullerDepartment of Pathology, Amsterdam Neuroscience, Amsterdam University Medical Center, Free University Amsterdam, The Netherlands.
Philip ScheltensDepartment of Clinical Chemistry, The Alzheimer Center Amsterdam, and Neurochemistry Laboratory, Amsterdam Neuroscience, Amsterdam University Medical Center, Free University Amsterdam, The Netherlands.
Jochen WalterDepartment of Neurology, University of Bonn, Bonn, Germany.
Eric J G SijbrandsDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Pilar Martinez-MartinezDepartment of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Adrie J M VerhoevenDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Charlotte E TeunissenDepartment of Clinical Chemistry, The Alzheimer Center Amsterdam, and Neurochemistry Laboratory, Amsterdam Neuroscience, Amsterdam University Medical Center, Free University Amsterdam, The Netherlands.
Monique T MulderDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Erasmus MC · NLAmsterdam Neuroscience · NLMaastricht University · NLUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Alzheimer's disease (AD) patients display alterations in cerebrospinal fluid (CSF) and plasma sphingolipids. The Objective: To test the hypothesis that the Methods: Patients homozygous for Results: Conclusion: The

Indexed as

Alzheimer’s diseaseamyloid-β peptidesApolipoprotein E4ceramidescerebrospinal fluidcognitive dysfunctionlipoproteinssphingolipids

Identifiers

PMID37220621
PMCPMC10200192
OpenAlexW4324138384

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.