Evidence map›Paper›PMID 37220320›Full record

Observational studyJCO oncology practice2023

On-Site Nurse-Led Cancer Genetics Program Increases Cancer Genetic Testing Completion in Black Veterans.

Jeffrey W Shevach, Lisa B Aiello, Julie A Lynch, Jeffrey Petersen, Lori Hoffman-Hogg, Deborah Hartzfeld, Margaret Lundquist, Michael J Kelley, Maren T Scheuner, Robert Montgomery and 6 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Barriers and Facilitators Influencing Nurses in Genetic Services Provision: A Systematic Review.Nigerian medical journal : journal of the Nigeria Medical Association
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Jeffrey W ShevachCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.ORCID 0000-0002-3982-781X
Lisa B AielloCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.
Julie A LynchGeorge E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT.ORCID 0000-0003-0108-2127
Jeffrey PetersenCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.
Lori Hoffman-HoggVeterans Health Administration National Center for Health Promotion and Disease Prevention, Durham, NC.
Deborah HartzfeldGeorge E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT.ORCID 0000-0002-0127-8114
Margaret LundquistGeorge E. Whalen Veterans Affairs Medical Center, Salt Lake City, UT.
Michael J KelleyDurham VA Medical Center, Durham, NC.ORCID 0000-0001-9523-6080
Maren T ScheunerSan Francisco Veterans Affairs Health Care System, San Francisco, CA.ORCID 0000-0002-9105-1369
Robert MontgomeryDivision of Medical Oncology, University of Washington and Seattle Cancer Care Alliance, Seattle, WA.ORCID 0000-0003-4459-0295
Nevena DamjanovCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.ORCID 0000-0002-4195-7277
Kyle RobinsonCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.
Yu-Ning WongCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.
Darshana JhalaCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.
Ravi B ParikhCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.
Kara N MaxwellCorporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA.ORCID 0000-0003-2692-6306
Veterans Health Administration · USPhiladelphia VA Medical Center · USDuke University · USSan Francisco VA Medical Center · USSeattle Cancer Care Alliance · USUnited States Department of Veterans Affairs · USUniversity of Utah · US

Funding

CANCER CLINICAL EPIDEMIOLOGY TRAINING GRANTT32CA009679 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Richard Aplenc, Karen Glanz · 1992 to 2026
$11.1M
Postdoctoral Training Program in Genomic MedicineT32HG009495 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI Katherine L. Nathanson, Bogdan Pasaniuc · 2017 to 2026
$4.2M
A genotype-phenotype study of tumors from patients with inherited mutations in DNA repair genesK08CA215312 · NCI · UNIVERSITY OF PENNSYLVANIA · PI MAXWELL, KARA N · 2018 to 2022
$924k
NCI NIH HHS K08 CA215312NCI NIH HHS T32 CA009679NHGRI NIH HHS T32 HG009495
6 · The paper itself

Abstract

purposeTelegenetics services can expand access to guideline-recommended cancer genetic testing. However, access is often not distributed equitably to all races and ethnicities. We evaluated the impact of an on-site nurse-led cancer genetics service in a diverse Veterans Affairs Medical Center (VAMC) oncology clinic on likelihood of germline testing (GT) completion.

methodsWe conducted an observational retrospective cohort study of patients who were referred for cancer genetics services at the Philadelphia VAMC between October 1, 2020, and February 28, 2022. We evaluated the association between genetics service (on-site

resultsA total of 238 Veterans, including 108 (45%) seen on site, were identified for cancer genetics services during the study period, with the majority referred for a personal (65%) or family (26%) history of cancer. In the subcohort of new consults, 121 Veterans (54% self-identified race/ethnicity [SIRE]-Black), including 60 (50%) seen on site, were included in the analysis of germline genetic testing completion. In a univariate analysis, patients who were seen by the on-site genetics service had 3.2-fold higher likelihood of completing GT (relative risk, 3.22; 95% CI, 1.89 to 5.48) compared with the telegenetics service. In multivariable regression analysis, the on-site genetics service was associated with higher likelihood of GT completion, but this association was only statistically significant in SIRE-Black compared with SIRE-White Veterans (adjusted RR, 4.78; 95% CI, 1.53 to 14.96;

conclusionAn on-site nurse-led cancer genetics service embedded in a VAMC Oncology practice was associated with higher likelihood of germline genetic testing completion than a telegenetics service among self-identified Black Veterans.

Indexed as

NeoplasmsVeteransGenetic TestingHumansNurse's RoleRetrospective Studies

Identifiers

PMID37220320
PMCPMC10424905
OpenAlexW4377693753

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.