Evidence map›Paper›PMID 37219997›Full record

ArticleThe journal of physical chemistry. B2023

Computational Study of Base-Catalyzed Thiohemiacetal Decomposition in

Himani N Patel, Brandon E Haines, Cynthia V Stauffacher, Paul Helquist, Olaf Wiest

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physical chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Himani N PatelDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Brandon E HainesDepartment of Chemistry, Westmont College, Santa Barbara, California 93108, United States.ORCID 0000-0002-5013-8396
Cynthia V StauffacherDepartment of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, United States.
Paul HelquistDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0003-4380-9566
Olaf WiestDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0001-9316-7720
University of Notre Dame · USPurdue University West Lafayette · USWestmont College · US

Funding

Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
Determination of structure, dynamics and energetics of enzyme reactionsR01GM111645 · NIGMS · UNIVERSITY OF NOTRE DAME · PI WIEST, OLAF G · 2015 to 2023
$2.5M
NIGMS NIH HHS R01 GM111645NIGMS NIH HHS T32 GM075762
6 · The paper itself

Abstract

Thiohemiacetals are key intermediates in the active sites of many enzymes catalyzing a variety of reactions. In the case of

Indexed as

Acyl Coenzyme APseudomonasCatalysisCatalytic DomainKinetics3-hydroxy-3-methylglutaryl-coenzyme AAcyl Coenzyme A

Identifiers

PMID37219997
PMCPMC11607680
OpenAlexW4377826061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.