Evidence map›Paper›PMID 37219590›Full record

ArticleActa crystallographica. Section D, Structural biology2023

Analysis and validation of overall N-glycan conformation in Privateer.

Jordan S Dialpuri, Haroldas Bagdonas, Mihaela Atanasova, Lucy C Schofield, Maarten L Hekkelman, Robbie P Joosten, Jon Agirre

Abstract read
In one paragraph

Article in Acta crystallographica. Section D, Structural biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Avoiding pitfalls when modelling ligands in macromolecular crystallography.Acta crystallographica. Section D, Structural biology · 2026
    Article
  2. Article
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  6. Article
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  10. Article
  11. Post-translational modifications in the Protein Data Bank.Acta crystallographica. Section D, Structural biology · 2024
    Review
  12. Online carbohydrate 3D structure validation with the Privateer web app.Acta crystallographica. Section F, Structural biology communications · 2024
    Article
  13. Monitoring carbohydrate 3D structure quality with theBeilstein journal of organic chemistry · 2024
    Article
  14. The CCP4 suite: integrative software for macromolecular crystallography.Acta crystallographica. Section D, Structural biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jordan S DialpuriYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0002-6205-2661
Haroldas BagdonasYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0001-5028-4847
Mihaela AtanasovaYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0003-0892-6687
Lucy C SchofieldYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.
Maarten L HekkelmanOncode Institute and Division of Biochemistry, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-9081-4707
Robbie P JoostenOncode Institute and Division of Biochemistry, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-2323-2686
Jon AgirreYork Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.ORCID 0000-0002-1086-0253

Funding

Biotechnology and Biological Sciences Research Council BB/T0072221
6 · The paper itself

Abstract

The oligosaccharides in N-glycosylation provide key structural and functional contributions to a glycoprotein. These contributions are dependent on the composition and overall conformation of the glycans. The Privateer software allows structural biologists to evaluate and improve the atomic structures of carbohydrates, including N-glycans; this software has recently been extended to check glycan composition through the use of glycomics data. Here, a broadening of the scope of the software to analyse and validate the overall conformation of N-glycans is presented, focusing on a newly compiled set of glycosidic linkage torsional preferences harvested from a curated set of glycoprotein models.

Indexed as

OligosaccharidesPolysaccharidesCarbohydrate ConformationGlycomicsGlycoproteinsGlycosylationGlycoproteinsOligosaccharidesPolysaccharidesglycobiologyN-glycansPrivateertorsion anglesvalidation

Identifiers

PMID37219590
PMCPMC10233620

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.