ArticleAnalytical and bioanalytical chemistry2023
Comparing derivatization reagents for quantitative LC-MS/MS analysis of a variety of vitamin D metabolites.
Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Systematic Optimization of an SLE-DAPTAD LC-MS/MS Workflow for Simultaneous Quantification of Low-Abundance Vitamin DRapid communications in mass spectrometry : RCM · 2026Article
- A Click-Type Reaction of (RRR)-α-Tocopherol and Related 6-Chromanols Allowing a One Pot Derivatisation of All Fat-Soluble Vitamins.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Lab-in-a-Droplet: Utilizing Acoustic Levitation for Miniaturized Sample Preparation and LC-MS/MS, Exemplified by Measurement of Vitamin D in Serum.Analytical chemistry · 2026Article
- Vitamin D in Photosynthetic Organisms and Fungi: Sterol Photochemistry, UV-B Availability, and Biofortification Potential.Current issues in molecular biology · 2026Review
- Evaluation of correlations between serum and urinary vitamin D metabolites using LC-MS/MS.Bioscience reports · 2026Article
- A rapid LC-MS/MS method with 2-nitrosopyridine derivatization to determine fat-soluble vitamins, revealing a biphasic bile acids association in clinical cohorts.Analytical and bioanalytical chemistry · 2026Article
- Quantification of the Kynurenine Biomarker in Saliva Using Smatphone-Based Fluorescence Digital Imaging.ACS omega · 2026Article
- High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules.Analytical chemistry · 2026Article
- Value Assignment of Vitamin D and 25-Hydroxyvitamin D in Food-Matrix Standard Reference Materials (SRMs) Using Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry (ID LC-MS/MS).Journal of agricultural and food chemistry · 2026Article
- Harnessing natural sunlight indoors: sensor-regulated therapeutic approach to enhance vitamin D status in humans.Scientific reports · 2026Article
- Quantification of 24,25-Dihydroxyvitamin DInternational journal of analytical chemistry · 2026Article
- Streamlined Vitamin D Metabolite Fingerprinting Analysis Using Isotope-Coded Multiplexing MS with Cost-Effective One-Pot Double Derivatization.ACS omega · 2024Article
- Review
- A novel LC-MS/MS method combined with derivatization for simultaneous quantification of vitamin D metabolites in human serum with diabetes as well as hyperlipidemia.RSC advances · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The present study systematically compares the sensitivity and selectivity of the analysis of multiple vitamin D metabolites after chemical derivatization using different reagents for liquid chromatography-tandem mass spectrometry (LC-MS/MS). Generally, chemical derivatization is applied to vitamin D metabolites to increase the ionization efficiency, which is particularly important for very low abundant metabolites. Derivatization can also improve the selectivity of the LC separation. A wide variety of derivatization reagents has been reported in recent years, but information on their relative performance and applicability to different vitamin D metabolites is, unfortunately, not available in the literature. To fill this gap, we investigated vitamin D
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