Evidence map›Paper›PMID 37219390›Full record

ArticleCNS oncology2023

HER2+ esophageal carcinoma leptomeningeal metastases treated with intrathecal trastuzumab regimen.

Scott A Wu, Dan Tong Jia, Margaret Schwartz, Mary Mulcahy, Kuanghua Guo, Matthew C Tate, Sean Sachdev, Nicolas Kostelecky, David J Escobar, Daniel J Brat and 2 more

Open access · goldAbstract read
In one paragraph

Article in CNS oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Leptomeningeal Disease: Current Approaches and Future Directions.Current neurology and neuroscience reports · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Scott A WuNorthwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-0440-1218
Dan Tong JiaDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Lou & Jean Malnati Brain Tumor Institute, Chicago, IL 60611, USA.
Margaret SchwartzDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Lou & Jean Malnati Brain Tumor Institute, Chicago, IL 60611, USA.
Mary MulcahyDepartment of Hematology & Oncology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Kuanghua GuoDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Lou & Jean Malnati Brain Tumor Institute, Chicago, IL 60611, USA.
Matthew C TateDepartment of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Sean SachdevDepartment of Radiation Oncology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Nicolas KosteleckyDepartment of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
David J EscobarDepartment of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-8322-8451
Daniel J BratDepartment of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Amy B HeimbergerDepartment of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
Rimas V LukasDepartment of Neurology, Northwestern University, Feinberg School of Medicine, Lou & Jean Malnati Brain Tumor Institute, Chicago, IL 60611, USA.ORCID 0000-0002-9352-5396
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsCarcinomaMeningeal CarcinomatosisAntineoplastic Combined Chemotherapy ProtocolsErb-b2 Receptor Tyrosine KinasesFemaleHumansRetrospective StudiesTrastuzumabErb-b2 Receptor Tyrosine KinasesTrastuzumabcirculating tumor cellsesophageal cancerHER2intrathecalleptomeningeal metastasestrastuzumab

Identifiers

PMID37219390
PMCPMC10410688
OpenAlexW4377565625

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.