Evidence map›Paper›PMID 37219322›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

CEACAM6 as a Novel Therapeutic Target to Boost HO-1-mediated Antioxidant Defense in COPD.

Cheng-Yu Wu, Anis Cilic, Oleg Pak, Ruth Charlotte Dartsch, Jochen Wilhelm, Magdalena Wujak, Kevin Lo, Monika Brosien, Ruoyu Zhang, Ibrahim Alkoudmani and 13 more

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  10. METTL16 suppresses ferroptosis in cholangiocarcinoma by promoting ATF4 via mInternational journal of biological sciences · 2025
    Article
  11. Review
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  16. CEACAM6: A Novel Marker of Chronic Obstructive Pulmonary Disease Susceptibility?American journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 2 countries.

Cheng-Yu WuExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.ORCID 0000-0002-2788-8586
Anis CilicExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Oleg PakExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Ruth Charlotte DartschExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Jochen WilhelmExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Magdalena WujakExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Kevin LoExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Monika BrosienExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Ruoyu ZhangDepartment of General and Thoracic Surgery, University Hospital of Giessen, Giessen, Germany.
Ibrahim AlkoudmaniDepartment of General and Thoracic Surgery, University Hospital of Giessen, Giessen, Germany.
Biruta WitteDepartment of General and Thoracic Surgery, University Hospital of Giessen, Giessen, Germany.
Frauke PedersenPulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North, DZL, Grosshansdorf, Germany.
Henrik WatzPulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North, DZL, Grosshansdorf, Germany.
Robert VoswinckelHealth Center Wetterau, Bad Nauheim, Germany.
Andreas GüntherExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Hossein A GhofraniExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Ralf P BrandesInstitute for Cardiovascular Physiology, Goethe University, Frankfurt am Main, Germany; and.
Ralph T SchermulyExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Friedrich GrimmingerExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Werner SeegerExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Natascha SommerExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.
Norbert WeissmannExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.ORCID 0000-0003-2675-3871
Stefan HadzicExcellence Cluster Cardio-Pulmonary Institute, Universities of Giessen and Marburg Lung Center, member of the German Center for Lung Research (DZL), Justus Liebig University Giessen, Giessen, Germany.ORCID 0000-0001-8459-2776
Justus-Liebig-Universität Gießen · DEUniversitätsklinikum Gießen und Marburg · DELungenClinic Grosshansdorf · DEGoethe University Frankfurt · DEKerckhoff Klinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EmphysemaPulmonary Disease, Chronic ObstructivePulmonary EmphysemaAntigens, CDAntioxidantsCell Adhesion MoleculesGPI-Linked ProteinsHeme Oxygenase-1HumansNicotianaOxidative StressAntigens, CDAntioxidantsCEACAM6 protein, humanCell Adhesion MoleculesGPI-Linked ProteinsHeme Oxygenase-1HMOX1 protein, human3-nitrotyrosineantioxidant defensecigarette smokeCOPDlung emphysema

Identifiers

PMID37219322
OpenAlexW4377565346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.