Evidence map›Paper›PMID 37218991›Full record

ArticleNon-coding RNA2023

Genetic Deletion of the

Xiaofang Tang, Chih-Hung Lai, Naseeb K Malhi, Rahuljeet Chadha, Yingjun Luo, Xuejing Liu, Dongqiang Yuan, Alonso Tapia, Maryam Abdollahi, Guangyu Zhang and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Non-coding RNA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Role of eRNAs in Cardiovascular Diseases.Current cardiology reviews · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Xiaofang TangDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Chih-Hung LaiDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.ORCID 0000-0003-1409-4979
Naseeb K MalhiDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Rahuljeet ChadhaDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Yingjun LuoDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Xuejing LiuDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Dongqiang YuanDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Alonso TapiaDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Maryam AbdollahiDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Guangyu ZhangDepartment of Diabetes and Cancer Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
Riccardo CalandrelliDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-4541-6320
Yan-Ting ShiuDivision of Nephrology & Hypertension, University of Utah, Salt Lake City, UT 84132, USA.ORCID 0000-0001-5881-8268
Zhao V WangIrell and Manella Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.ORCID 0000-0002-9904-9538
June-Wha RheeDepartment of Medicine, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
Sheng ZhongDepartment of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA.
Rama NatarajanDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.ORCID 0000-0003-4494-1788
Zhen Bouman ChenDepartment of Diabetes Complications and Metabolism, Arthur Riggs Diabetes Metabolism Research Institute and Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.
City of Hope · USUniversity of California San Diego · USCalifornia Institute of Technology · USNational Yang Ming Chiao Tung University · TWUniversity of Utah · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
Inflammatory Gene Transcription In Diabetic ConditionsR01DK065073 · NIDDK · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI NATARAJAN, RAMA · 2003 to 2021
$7.9M
Transcriptional Regulation by Angiotensin II in Vascular Smooth Muscle CellsR01HL106089 · NHLBI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NATARAJAN, RAMA · 2011 to 2024
$6.6M
Transforming growth factor beta1, microRNAs, lncRNA and diabetic nephropathyR01DK081705 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NATARAJAN, RAMA · 2009 to 2023
$6.1M
Long non-coding RNA-mediated chromatin remodeling in angiogenesisR01HL145170 · NHLBI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, ZHEN BOUMAN · 2019 to 2023
$2.6M
Revealing protein-protein interactions and RNA-protein interactions at genome-scale in two weeksR01GM138852 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZHONG, SHENG · 2020 to 2023
$1.5M
A low-input microfluidic ChIRP-seq technology for studying endogenous lncRNA bindingR01GM141096 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LU, CHANG · 2021 to 2024
$1.1M
Patient-specific modeling of metabolic dysfunction in statin-induced myopathy using iPSC-derived myocytesK08HL148540 · NHLBI · STANFORD UNIVERSITY · PI RHEE, JUNE-WHA · 2020 to 2024
$760k
NCI NIH HHS P30 CA033572NCI NIH HHS P30CA033572NHLBI NIH HHS K08 HL148540NHLBI NIH HHS R01 HL106089NHLBI NIH HHS R01 HL145170NIDDK NIH HHS R01 DK065073NIDDK NIH HHS R01 DK081705NIGMS NIH HHS R01 GM138852NIGMS NIH HHS R01 GM141096NIH HHS K08HL148540NIH HHS R01GM141096NIH HHS R01 HL106089NIH HHS R01 HL145170
6 · The paper itself

Abstract

(1) Background: Hypertension is a complex, multifactorial disease that is caused by genetic and environmental factors. Apart from genetic predisposition, the mechanisms involved in this disease have yet to be fully understood. We previously reported that LEENE (lncRNA enhancing endothelial nitric oxide expression, transcribed from

Indexed as

ECshypertensionLEENELncRNA

Identifiers

PMID37218991
PMCPMC10204496
OpenAlexW4376956937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.