Evidence map›Paper›PMID 37218981›Full record

ReviewNeurology international2023

Exploring the Utility of Autonomic Nervous System Evaluation for Stroke Prognosis.

Ilias Orgianelis, Ermis Merkouris, Sofia Kitmeridou, Dimitrios Tsiptsios, Stella Karatzetzou, Anastasia Sousanidou, Aimilios Gkantzios, Foteini Christidi, Efthymia Polatidou, Anastasia Beliani and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Neurology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Heart Meets Brain: Insights into Neurocardiac Pathophysiology.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Ilias OrgianelisNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Ermis MerkourisNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Sofia KitmeridouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Dimitrios TsiptsiosNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-1601-8788
Stella KaratzetzouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Anastasia SousanidouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-2092-6313
Aimilios GkantziosNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0002-0890-4069
Foteini ChristidiNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Efthymia PolatidouNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Anastasia BelianiNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Anna TsiakiriNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-3341-4093
Christos KokkotisDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.
Stylianos IliopoulosDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.
Konstantinos AnagnostopoulosDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.
Nikolaos AggelousisDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, Greece.ORCID 0000-0001-5108-7335
Konstantinos VadikoliasNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0003-0484-369X
Democritus University of Thrace · GR

Funding

EYD-EPANEK MIS 5047286
6 · The paper itself

Abstract

Stroke is a major cause of functional disability and is increasing in frequency. Therefore, stroke prognosis must be both accurate and timely. Among other biomarkers, heart rate variability (HRV) is investigated in terms of prognostic accuracy within stroke patients. The literature research of two databases (MEDLINE and Scopus) is performed to trace all relevant studies published within the last decade addressing the potential utility of HRV for stroke prognosis. Only the full-text articles published in English are included. In total, forty-five articles have been traced and are included in the present review. The prognostic value of biomarkers of autonomic dysfunction (AD) in terms of mortality, neurological deterioration, and functional outcome appears to be within the range of known clinical variables, highlighting their utility as prognostic tools. Moreover, they may provide additional information regarding poststroke infections, depression, and cardiac adverse events. AD biomarkers have demonstrated their utility not only in the setting of acute ischemic stroke but also in transient ischemic attack, intracerebral hemorrhage, and traumatic brain injury, thus representing a promising prognostic tool whose clinical application may greatly facilitate individualized stroke care.

Indexed as

autonomic dysfunctionautonomic nervous systemheart rate variabilitystroke outcomestroke prognosis

Identifiers

PMID37218981
PMCPMC10204362
OpenAlexW4377108049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.