Evidence map›Paper›PMID 37218960›Full record

ArticleVision (Basel, Switzerland)2023

Amblyopia Treatment through Immersive Virtual Reality: A Preliminary Experience in Anisometropic Children.

Ainhoa Molina-Martín, Luis Leal-Vega, Dolores de Fez, Elena Martínez-Plaza, María Begoña Coco-Martín, David P Piñero

Open access · goldAbstract readCase Reports
In one paragraph

Article in Vision (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Review
  3. Prospective observational study of three real-world amblyopia treatments in children: clinical outcomes and predictive factors.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Observational
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ainhoa Molina-MartínGroup of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente del Raspeig, Spain.ORCID 0000-0003-4854-3592
Luis Leal-VegaDepartment of Medicine, Dermatology and Toxicology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.ORCID 0000-0002-7847-413X
Dolores de FezGroup of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente del Raspeig, Spain.ORCID 0000-0003-4404-8236
Elena Martínez-PlazaGroup of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente del Raspeig, Spain.
María Begoña Coco-MartínDepartment of Medicine, Dermatology and Toxicology, Faculty of Medicine, University of Valladolid, 47003 Valladolid, Spain.ORCID 0000-0001-9977-429X
David P PiñeroGroup of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, 03690 San Vicente del Raspeig, Spain.ORCID 0000-0002-1546-4807
Universidad de Valladolid · ESUniversity of Alicante · ES

Funding

Centre for Industrial Technological Development Project NEIVATECH (Neuroplasticity through Virtual Reality for Amblyopia) with the grant number 111705European Commission European Union-NextGenerationEU
6 · The paper itself

Abstract

The use of digital devices provides a wide range of possibilities for measuring and improving visual function, including concepts such as perceptual learning and dichoptic therapy. Different technologies can be used to apply these concepts, including, in recent years, the introduction of virtual reality (VR) systems. A preliminary experience in treating anisometropic amblyopia through an immersive VR device and using prototype software is described. A total of 4 children were treated by performing 18 office-based sessions. Results showed that distance VA in amblyopic eyes remained constant in two subjects, whereas the younger subjects improved after the training. Near VA improved in three subjects. All subjects showed an increase in the stereopsis of at least one step, with three subjects showing a final stereopsis of a 60 s arc. A total of three subjects showed an increase of approximately 0.5 CS units for the spatial frequency of 3 cpd after the training. Results from this pilot study suggest that visual training based on perceptual learning through an immersive VR environment could be a viable treatment for improving CS, VA, and stereopsis in some children with anisometropic amblyopia. Future studies should support these preliminary results.

Indexed as

amblyopiaanisometropicchildrendichoptic trainingperceptual learningvirtual realityvision therapy

Identifiers

PMID37218960
PMCPMC10204412
OpenAlexW4377289816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.