Evidence map›Paper›PMID 37218688›Full record

Trial reportWomen's health (London, England)

Emotion dysregulation is heightened in autistic females: A comparison with autistic males and borderline personality disorder.

Luisa Weiner, Madalina Elena Costache, Doha Bemmouna, Juliette Rabot, Sébastien Weibel, Marine Dubreucq, Julien Dubreucq, Romain Coutelle

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04737707 (Dialectical Behavior Therapy for Adults With Autism Spectrum Disorders Without Intellectual Disability), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04737707 nacompletednot on this map

Dialectical Behavior Therapy for Adults With Autism Spectrum Disorders Without Intellectual Disability: a Randomized Controlled Trial

TypeinterventionalSponsorUniversity Hospital, Strasbourg, FranceRan2021 to 2025Enrolled92ConditionsAutism Spectrum DisordersArmsDialectical Behavior Therapy (DBT)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Autistic Traits and Camouflaging: A Meta-Analysis.Autism : the international journal of research and practice · 2026
    Pooled it
  2. Article
  3. Article
  4. Lifetime stressor exposure is related to suicidality in autistic adults: A multinational study.Autism : the international journal of research and practice · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Luisa WeinerLaboratoire de Psychologie des Cognitions, Faculté de Psychologie, Université de Strasbourg, Strasbourg, France.ORCID 0000-0002-1178-5929
Madalina Elena CostacheLaboratoire de Psychologie des Cognitions, Faculté de Psychologie, Université de Strasbourg, Strasbourg, France.
Doha BemmounaLaboratoire de Psychologie des Cognitions, Faculté de Psychologie, Université de Strasbourg, Strasbourg, France.
Juliette RabotDepartment of Psychiatry, University Hospital of Strasbourg, Strasbourg, France.
Sébastien WeibelDepartment of Psychiatry, University Hospital of Strasbourg, Strasbourg, France.
Marine DubreucqCentre référent de réhabilitation psychosociale et de Remédiation Cognitive (C3R), Centre Hospitalier Alpes Isère, Grenoble, France.
Julien DubreucqCentre référent de réhabilitation psychosociale et de Remédiation Cognitive (C3R), Centre Hospitalier Alpes Isère, Grenoble, France.
Romain CoutelleDepartment of Psychiatry, University Hospital of Strasbourg, Strasbourg, France.
Université de Strasbourg · FRInserm · FRFondation FondaMental · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmotion dysregulation is increasingly recognized as highly prevalent and impairing in autistic individuals. Yet, a large majority of studies have considered emotion dysregulation in youth only, and most of them did not consider sex differences in emotion dysregulation manifestation.

objectivesIn the present study, we aim to investigate sex differences relative to emotion dysregulation in autistic adults without intellectual disability as well as its relationship with different factors potentially involved in emotion dysregulation (e.g. camouflaging, alexithymia, suicidality, quality of life). Self-reported emotion dysregulation will be assessed in autistic adults but also in females with borderline personality disorder, given that emotion dysregulation is particularly enhanced in this population.

designCross-sectional, prospective, controlled.

methodsTwenty-eight autistic females, 22 autistic males and 24 females with borderline personality disorder were recruited from a dialectical behavior therapy program waiting list. They completed several self-report questionnaires measuring emotion dysregulation, alexithymia, suicidality, quality of life, camouflaging borderline symptoms and autism severity.

resultsMost emotion dysregulation subscale scores and alexithymia scores were heightened in autistic females compared to females with borderline personality disorder and, to a lesser extent, compared to autistic males. Independently of borderline personality disorder symptoms, emotion dysregulation was related to alexithymia and poorer psychological health in autistic females, whereas it was mostly related to autism severity, poorer physical health and living conditions in autistic males.

conclusionOur results suggest that emotion dysregulation is a major difficulty of autistic adults without intellectual disability eligible for dialectical behavior therapy, and this is especially the case for autistic females. There seem to be different sex-specific factors involved in emotion dysregulation found in autistic adults, which highlight the need to target-specific domains (e.g. alexithymia) in the treatment of emotion dysregulation in autistic females. ClinicalTrials.gov Identifier: NCT04737707 https://clinicaltrials.gov/ct2/show/NCT04737707.

Indexed as

Autistic DisorderBorderline Personality DisorderIntellectual DisabilityAdolescentAdultCross-Sectional StudiesEmotionsFemaleHumansMaleProspective StudiesQuality of Lifealexithymiaautism spectrum disorderborderline personality disorderemotion dysregulationmental healthsex differences

Identifiers

PMID37218688
PMCPMC10214106
OpenAlexW4377563862

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.