ArticleTherapeutic advances in respiratory disease
Predictors of poor clinical outcomes including in-hospital death and low ability to perform activities of daily living at discharge in hospitalized patients with chronic obstructive pulmonary disease exacerbation.
Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Diaphragmatic Thickening Fraction and Excursion: Different Clinical Values in Non-Critically Ill Patients with AECOPD - An Exploratory Study.International journal of chronic obstructive pulmonary disease · 2026Observational
- The cross-sectional area of the erector spinae muscle is an adverse indicator for patient with acute exacerbation of chronic obstructive pulmonary disease.Scientific reports · 2025Article
- Predictors of Clinical Stability and Mortality in COPD: A Longitudinal Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Poor treatment outcomes of acute exacerbations of chronic obstructive pulmonary disease and their associated factors among admitted patients in East Gojjam, 2023.Frontiers in medicine · 2024Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic obstructive pulmonary disease (COPD) is a major cause of mortality and morbidity worldwide. Many patients with COPD experience exacerbations that require hospitalization, which is associated with an increased risk of in-hospital death and impaired ability to perform activities of daily living (ADL). Declining ability to perform ADL is a critical issue for these patients.
objectivesTo identify predictors of poor clinical outcomes, including in-hospital death and low ability to perform ADL at discharge, in patients who are hospitalized with exacerbation of COPD.
designThis retrospective study involved a cohort of patients with exacerbation of COPD who were admitted to Iwata City Hospital in Japan between July 2015 and October 2019.
methodsWe collected clinical data, measured the cross-sectional area of the erector spinae muscles (ESM
resultsOverall, 207 patients were hospitalized for exacerbation of COPD during the study period. The incidence of poor clinical outcomes was 21.3%, and the in-hospital mortality rate was 6.3%. Multivariate logistic regression analyses showed that older age, long-term oxygen therapy, an elevated D-dimer concentration, and a reduced ESM
conclusionHospitalization for exacerbation of COPD was associated with high rates of in-hospital mortality and a BI of ⩽40 at discharge, which may be predicted by assessment of ESM
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