Observational studyJournal of the American Heart Association2023
Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging.
Observational study in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Diagnostic performance of ultra-low field neurological magnetic resonance imaging: a systematic review protocol.BMJ open · 2026Article
- Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort.Annals of clinical and translational neurology · 2026Article
- Portable Low-Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus.Annals of clinical and translational neurology · 2026Article
- Enhanced Detection of Acute Ischemic Stroke With Low-Field MRI.Stroke (Hoboken, N.J.) · 2026Article
- Breast imaging with ultra-low field MRI.Scientific reports · 2026Article
- Detecting patterns of atrophy in cognitively impaired individuals using portable, low-field MRI.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Ultra-low-field MRI: a David versus Goliath challenge in modern imaging.La Radiologia medica · 2025Review
- Portable Bedside Low-Field MRI for Assessment of Ventricular Size.AJNR. American journal of neuroradiology · 2025Article
- Predicting White Matter Hyperintensity: Leveraging Portable MRI for Accessible Brain Health Screening.AJNR. American journal of neuroradiology · 2025Article
- Field-cycling imaging yields repeatable brain RMagma (New York, N.Y.) · 2025Article
- Portable, low-field magnetic resonance imaging for evaluation of Alzheimer's disease.Nature communications · 2024Article
- Low-Field (64 mT) Portable MRI for Rapid Point-of-Care Diagnosis of Dissemination in Space in Patients Presenting with Optic Neuritis.AJNR. American journal of neuroradiology · 2024Article
- Enhancing organ and vascular contrast in preclinical ultra-low field MRI using superparamagnetic iron oxide nanoparticles.Communications biology · 2024Article
- Toward Next-Generation Molecular Imaging with a Clinical Low-Field (0.064 T) Point-of-Care MRI Scanner.Analytical chemistry · 2024Article
- QUANTIFYING WHITE MATTER HYPERINTENSITY AND BRAIN VOLUMES IN HETEROGENEOUS CLINICAL AND LOW-FIELD PORTABLE MRI.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024Article
- Brain imaging with portable low-field MRI.Nature reviews bioengineering · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
17 authors at 3 institutions in 1 country.
Funding
Abstract
Background White matter hyperintensity (WMH) on magnetic resonance imaging (MRI) of the brain is associated with vascular cognitive impairment, cardiovascular disease, and stroke. We hypothesized that portable magnetic resonance imaging (pMRI) could successfully identify WMHs and facilitate doing so in an unconventional setting. Methods and Results In a retrospective cohort of patients with both a conventional 1.5 Tesla MRI and pMRI, we report Cohen's kappa (κ) to measure agreement for detection of moderate to severe WMH (Fazekas ≥2). In a subsequent prospective observational study, we enrolled adult patients with a vascular risk factor being evaluated in the emergency department for a nonstroke complaint and measured WMH using pMRI. In the retrospective cohort, we included 33 patients, identifying 16 (49.5%) with WMH on conventional MRI. Between 2 raters evaluating pMRI, the interrater agreement on WMH was strong (κ=0.81), and between 1 rater for conventional MRI and the 2 raters for pMRI, intermodality agreement was moderate (κ=0.66, 0.60). In the prospective cohort we enrolled 91 individuals (mean age, 62.6 years; 53.9% men; 73.6% with hypertension), of which 58.2% had WMHs on pMRI. Among 37 Black and Hispanic individuals, the Area Deprivation Index was higher (versus White, 51.8±12.9 versus 37.9±11.9;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.