Evidence map›Paper›PMID 37218553›Full record

ArticleJournal of comparative effectiveness research2023

Network meta-analysis for indirect comparison of lanadelumab and berotralstat for the treatment of hereditary angioedema.

Maureen Watt, Mia Malmenäs, Dorothy Romanus, Katrin Haeussler

Open access · diamondAbstract readNetwork Meta-Analysis
In one paragraph

Article in Journal of comparative effectiveness research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. AnCurrent drug targets · 2026
    Article
  5. Article
  6. Indirect treatment comparison of oral sebetralstat and intravenous recombinant human C1 esterase inhibitor for on-demand treatment of hereditary angioedema attacks.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maureen WattTakeda Development Center Americas, Inc., Lexington, MA 02421, USA.ORCID 0000-0002-7868-2625
Mia MalmenäsICON plc, Stockholm, Sweden.
Dorothy RomanusTakeda Development Center Americas, Inc., Lexington, MA 02421, USA.
Katrin HaeusslerICON plc, Munich, Germany.
Takeda (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angioedemas, HereditaryAntibodies, Monoclonal, HumanizedHumansPyrazolesAntibodies, Monoclonal, HumanizedberotralstatlanadelumabPyrazolesberotralstatcomparative effectivenesshereditary angioedemaindirect treatment comparisonlanadelumabprophylaxis

Identifiers

PMID37218553
PMCPMC10402909
OpenAlexW4377564030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.