Evidence map›Paper›PMID 37218420›Full record

ReviewCancer science2023

Chromatin structure related to oncogenesis.

Syota Matsumoto, Naoki Horikoshi, Yoshimasa Takizawa, Hitoshi Kurumizaka

Open access · goldAbstract readReview
In one paragraph

Review in Cancer science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Syota MatsumotoLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8776-2096
Naoki HorikoshiLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-1842-6934
Yoshimasa TakizawaLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Hitoshi KurumizakaLaboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7412-3722
Quantitative BioSciences · US

Funding

Exploratory Research for Advanced Technology JPMJER1901Japan Agency for Medical Research and Development JP22ama121009Japan Society for the Promotion of Science JP18H05534Japan Society for the Promotion of Science JP20H00449Japan Society for the Promotion of Science JP22K06076Japan Society for the Promotion of Science JP22K06098Japan Society for the Promotion of Science JP22K18034Japan Society for the Promotion of Science JP23H05475Precursory Research for Embryonic Science and Technology JPMJPR2288The NOVARTIS Foundation for the Promotion of Science and Novartis Research GrantsThe Sumitomo Foundation and Basic Science Research Projects
6 · The paper itself

Abstract

Chromatin is the fundamental structure of genomic DNA in eukaryotic cells. The nucleosome, the primary unit of chromatin, consists of DNA and histone proteins, and is important for the maintenance of genomic DNA. Histone mutations are present in many types of cancers, suggesting that chromatin and/or nucleosome structures could be closely related to cancer development. Histone modifications and histone variants are also involved in regulating chromatin and nucleosome structures. Chromatin structures are dynamically changed by nucleosome binding proteins. In this review article, we discuss the current progress toward understanding the relationship between chromatin structure and cancer development.

Indexed as

HistonesNucleosomesCarcinogenesisChromatinDNAHumansChromatinDNAHistonesNucleosomeschromatinDNA repairhistone modificationhistone mutationnucleosome

Identifiers

PMID37218420
PMCPMC10394151
OpenAlexW4377565844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.