ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023
Subjective cognitive decline across ethnoracial groups in the A4 study.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- The Canadian multi-ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Observational
- Differences in cognitive performance and neuroanatomy according to Alzheimer's disease pathophysiology.Arquivos de neuro-psiquiatria · 2026Article
- Author's response to letter to the editor: "How culture shapes subjective cognitive decline reporting: Refining assessment tools with digital solutions".Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Clinical definition, biological characterization, and detection guidelines of subjective cognitive decline due to Alzheimer's disease and related dementia: A position paper from ISTAART SCD PIA.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Alzheimer Disease Biomarkers and Subjective Cognitive Decline Among Hispanic and/or Latino Adults.JAMA network open · 2025Article
- Subjective cognitive decline among diverse older adults: Prevalence and associations with objective cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Observational
- Sleep Apnea Risk, Subjective Cognitive Decline, and Cognitive Performance: Findings from the Boston Latino Aging Study.Dementia and geriatric cognitive disorders · 2025Article
- Subjective cognitive decline and cognitive change among diverse middle-aged and older Hispanic/Latino adults: Results from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Examining Demographic Factors, Psychosocial Wellbeing and Cardiovascular Health in Subjective Cognitive Decline in the Brain Health Registry Cohort.The journal of prevention of Alzheimer's disease · 2024Article
- Social determinants of health, genetic biomarkers, and cognitive function in Chinese older adults with subjective cognitive decline and mild cognitive impairment: A cross-sectional analysis.Journal of Alzheimer's disease reportsArticle
- Association of item-level responses to cognitive function index with tau pathology and hippocampal volume in the A4 Study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Characterizing Japanese older adults without dementia by amyloid PET status: A comparative study of amyloid-positive and amyloid-negative groups from Japanese trial-ready cohort study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Subjective memory concerns and AD/ADRD plasma biomarker associations in HABS-HD.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
introductionThe associations between subjective cognitive decline (SCD), cognition, and amyloid were explored across diverse participants in the A4 study.
methodsFive thousand one hundred and fifty-one non-Hispanic White, 262 non-Hispanic Black, 179 Hispanic-White, and 225 Asian participants completed the Preclinical Alzheimer Cognitive Composite (PACC), self- and study partner-reported Cognitive Function Index (CFI). A subsample underwent amyloid positron emission tomography (
resultsThe associations between PACC-CFI and amyloid-CFI were moderated by race. The relationships were weaker or non-significant in non-Hispanic Black and Hispanic White groups. Depression and anxiety scores were stronger predictors of CFI in these groups. Despite group differences in the types of study partners, self- and study partner-CFI were congruent across groups. DISCUSSION: SCD may not uniformly relate to cognition or AD biomarkers in different ethnoracial groups. Nonetheless, self- and study partner-SCD were congruent despite differences in study partner type. Highlights Association between SCD and objective cognition was moderated by ethnoracial group. Association between SCD and amyloid was moderated by ethnoracial group. Depression and anxiety were stronger predictors of SCD in Black and Hispanic groups. Study-partner and self-reported SCD are congruent across groups. Study-partner report was consistent despite difference in study partner types.
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