Evidence map›Paper›PMID 37217985›Full record

ArticleBMC complementary medicine and therapies2023

Assessment of antimicrobial and anthelmintic activity of silver nanoparticles bio-synthesized from Viscum orientale leaf extract.

Dugganaboyana Guru Kumar, Raghu Ram Achar, Jajur Ramanna Kumar, Ganamaedi Amala, Velliyur Kanniappan Gopalakrishnan, Sushma Pradeep, Ali A Shati, Mohammad Y Alfaifi, Serag Eldin I Elbehairi, Ekaterina Silina and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Dugganaboyana Guru KumarDivision of Biochemistry, School of Life Sciences, JSS Academy of Higher Education and Research (Deemed to Be University), Sri Shivarathreeshwara Nagara, Mysuru, 570015, Karnataka, India. gurukumard@jssuni.edu.in.
Raghu Ram AcharDivision of Biochemistry, School of Life Sciences, JSS Academy of Higher Education and Research (Deemed to Be University), Sri Shivarathreeshwara Nagara, Mysuru, 570015, Karnataka, India. rracharya@jssuni.edu.in.
Jajur Ramanna KumarDivision of Biochemistry, School of Life Sciences, JSS Academy of Higher Education and Research (Deemed to Be University), Sri Shivarathreeshwara Nagara, Mysuru, 570015, Karnataka, India.
Ganamaedi AmalaDivision of Biochemistry, School of Life Sciences, JSS Academy of Higher Education and Research (Deemed to Be University), Sri Shivarathreeshwara Nagara, Mysuru, 570015, Karnataka, India.
Velliyur Kanniappan GopalakrishnanSchool of Medicine, Bule Hora University Institute of Health, Bule Hora University, Bule Hora, Ethiopia.
Sushma PradeepDepartment of Biotechnology and Bioinformatics, JSS Academy of Higher Education, Mysore, India.
Ali A ShatiBiology Department, Faculty of Sciences, King Khalid University, Abha, Saudi Arabia.
Mohammad Y AlfaifiBiology Department, Faculty of Sciences, King Khalid University, Abha, Saudi Arabia.
Serag Eldin I ElbehairiBiology Department, Faculty of Sciences, King Khalid University, Abha, Saudi Arabia.
Ekaterina SilinaDepartment of Hospital Surgery, N.I. Pirogov Russian National Research Medical University (RNRMU), Moscow, 117 997, Russia.
Victor StupinDepartment of Hospital Surgery, N.I. Pirogov Russian National Research Medical University (RNRMU), Moscow, 117 997, Russia.
Natalia ManturovaDepartment of Hospital Surgery, N.I. Pirogov Russian National Research Medical University (RNRMU), Moscow, 117 997, Russia.
Chandan ShivamalluDepartment of Biotechnology and Bioinformatics, JSS Academy of Higher Education, Mysore, India. chandans@jssuni.edu.in.
Shiva Prasad KollurSchool of Physical Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, 570 026, Karnataka, India. shivachemist@gmail.com.
JSS Academy of Higher Education and Research · INKing Khalid University · SAPirogov Russian National Research Medical University · RUAmrita Vishwa Vidyapeetham · INBule Hora University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundViscum orientale is a largely used parasitic plant with traditional medicinal properties. They are considered to possess the medicinal properties of host tree which they grow on. It's a least explored plant with ethanopharmacological importance. As a result, the current work aimed to investigate the biological effects of Viscum orientale extract and silver nanoparticles (AgNPs) generated from it.

methodsAgNPs synthesized using Viscum orientale plant extract and analysed on time dependent series and was characterized using Ultra Violet UV-visible spectra, Fourier Transform Infrared Spectroscopy FTIR, X-ray diffraction (XRD), Energy Dispersive X-ray Spectroscopy (EDX), Scanning Electron Microscopy (SEM). Further using disc method anti-microbial assay was performed following antioxidation screening using 1,1-diphenyl-2-picryl-hydrazyl (DPPH), reducing power and nitric oxide content and heamgglutination with human blood.

resultsOn green synthesis using silver, the phyto contituents of plant Viscum orientale effectively reduced silver ions at 3-4 h of continuous stirring to form AgNPs. UV-vis spectra showed a typical peak of AgNPs at 480 nm. The FTIR analysis confirmed the covering of silver layers to bio-compounds of the extract. SEM analysis represented AgNPs as spherical morphologies ranging from 119-222 nm. AgNPs exhibited impressive zone of inhibition against Escherichia coli (8.1 ± 0.3 mm), Staphylococcus aureus (10.3 ± 0.3 mm), Bacillus subtilis (7.3 ± 0.3 mm), Bacillus cereus (8.2 ± 0.3 mm), Salmonella typhi (7.1 ± 0.2 mm). AgNps exhibited efficiency against DPPH at EC

conclusionSynthesized AgNPs using Viscum orientale water extract displayed versatile biological activity than individual extract. This study has forecasted a new path to explore more on this AgNPs for further research.

Indexed as

AnthelminticsAnti-Infective AgentsMetal NanoparticlesHumansNitric OxidePlant ExtractsSilverAnthelminticsAnti-Infective AgentsNitric OxidePlant ExtractsSilverAntihelmenthicAntimicrobialAnti-oxidationHemagglutinationSilver nanoparticlesViscum orientale

Identifiers

PMID37217985
PMCPMC10204336
OpenAlexW4377294198

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.