Evidence map›Paper›PMID 37217831›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Aerogel-Based Biomaterials for Biomedical Applications: From Fabrication Methods to Disease-Targeting Applications.

Solmaz Karamikamkar, Ezgi Pinar Yalcintas, Reihaneh Haghniaz, Natan Roberto de Barros, Marvin Mecwan, Rohollah Nasiri, Elham Davoodi, Fatemeh Nasrollahi, Ahmet Erdem, Heemin Kang and 8 more

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  5. Application of PLCL as a biodegradable polymer in biomedical engineering.Journal of materials science. Materials in medicine · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Solmaz KaramikamkarTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Ezgi Pinar YalcintasTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Reihaneh HaghniazTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Natan Roberto de BarrosTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Marvin MecwanTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Rohollah NasiriTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Elham DavoodiTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Fatemeh NasrollahiTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Ahmet ErdemDepartment of Biomedical Engineering, Kocaeli University, Umuttepe Campus, Kocaeli, 41001, Turkey.
Heemin KangDepartment of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.
Junmin LeeDepartment of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 37673, Republic of Korea.
Yangzhi ZhuTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Samad AhadianTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Vadim JucaudTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Hajar MalekiInstitute of Inorganic Chemistry, Department of Chemistry, University of Cologne, Greinstraße 6, 50939, Cologne, Germany.
Mehmet Remzi DokmeciTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.
Han-Jun KimTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.ORCID 0000-0001-9238-7238
Ali KhademhosseiniTerasaki Institute for Biomedical Innovation (TIBI), Los Angeles, CA, 90024, USA.ORCID 0000-0002-2692-1524

Funding

Drug eluting injectable biomaterials for next generation chemoembolizationR01CA257558 · NCI · MAYO CLINIC ARIZONA · PI KHADEMHOSSEINI, ALI, OKLU, RAHMI · 2021 to 2025
$3.2M
Hemorrhage control in the irreversible anticoagulated patientR01HL137193 · NHLBI · MAYO CLINIC ARIZONA · PI OKLU, RAHMI · 2017 to 2021
$3.0M
Treatment of arterial aneurysms using an injectable biomaterialR01HL140951 · NHLBI · MAYO CLINIC ARIZONA · PI KHADEMHOSSEINI, ALI, OKLU, RAHMI · 2018 to 2021
$2.6M
Healing enterocutaneous fistulas using bioengineered biomaterialsR01DK130566 · NIDDK · MAYO CLINIC ARIZONA · PI KHADEMHOSSEINI, ALI, OKLU, RAHMI · 2022 to 2025
$2.2M
NCI NIH HHS R01 CA257558NHLBI NIH HHS R01 HL137193NHLBI NIH HHS R01 HL140951NIDDK NIH HHS R01 DK130566NIH HHS CA257558NIH HHS DK130566NIH HHS HL137193NIH HHS HL140951
6 · The paper itself

Abstract

Aerogel-based biomaterials are increasingly being considered for biomedical applications due to their unique properties such as high porosity, hierarchical porous network, and large specific pore surface area. Depending on the pore size of the aerogel, biological effects such as cell adhesion, fluid absorption, oxygen permeability, and metabolite exchange can be altered. Based on the diverse potential of aerogels in biomedical applications, this paper provides a comprehensive review of fabrication processes including sol-gel, aging, drying, and self-assembly along with the materials that can be used to form aerogels. In addition to the technology utilizing aerogel itself, it also provides insight into the applicability of aerogel based on additive manufacturing technology. To this end, how microfluidic-based technologies and 3D printing can be combined with aerogel-based materials for biomedical applications is discussed. Furthermore, previously reported examples of aerogels for regenerative medicine and biomedical applications are thoroughly reviewed. A wide range of applications with aerogels including wound healing, drug delivery, tissue engineering, and diagnostics are demonstrated. Finally, the prospects for aerogel-based biomedical applications are presented. The understanding of the fabrication, modification, and applicability of aerogels through this study is expected to shed light on the biomedical utilization of aerogels.

Indexed as

Biocompatible MaterialsTissue EngineeringDesiccationWound HealingBiocompatible Materialsadditive manufacturingaerogeldiagnosisdrug deliverymicrofluidicstissue engineeringwound healing

Identifiers

PMID37217831
PMCPMC10427407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.