Evidence map›Paper›PMID 37217790›Full record

ReviewCancer gene therapy2023

Role of non-coding RNAs in neuroblastoma.

Ali Arash Anoushirvani, Arezoo Jafarian Yazdi, Sanaz Amirabadi, Sahar Ahmadi Asouri, Rana Shafabakhsh, Amirhossein Sheida, Maryam Sadat Hosseini Khabr, Ameneh Jafari, Seyed Saeed Tamehri Zadeh, Michael R Hamblin and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer gene therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. What is the Role of SNORA42 in Carcinogenesis? A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Ali Arash AnoushirvaniDepartment of Internal Medicine, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Arezoo Jafarian YazdiNeurology Department, Kashan University of Medical Sciences, Kashan, Iran.
Sanaz AmirabadiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Sahar Ahmadi AsouriResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University, Kashan, Iran.
Rana ShafabakhshResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University, Kashan, Iran.
Amirhossein SheidaSchool of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Maryam Sadat Hosseini KhabrSchool of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Ameneh JafariATMP Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, P.O. BOX: 15179/64311, Tehran, Iran.
Seyed Saeed Tamehri ZadehSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Michael R HamblinLaser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa.
Leila KalantariSchool of Medicine, Kashan University of Medical Sciences, Kashan, Iran. Leilakln284@gmail.com.
Sayyed Alireza Talaei ZavarehPhysiology Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran. talaeizavareh@gmail.com.
Hamed MirzaeiResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University, Kashan, Iran. h.mirzaei2002@gmail.com.ORCID http://orcid.org/0000-0002-9399-8281
Kashan University of Medical Sciences · IRAcademic Center for Education, Culture and Research · IRIran University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRTehran University of Medical Sciences · IRUniversity of Johannesburg · ZAUniversity of Kashan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma is known as the most prevalent extracranial malignancy in childhood with a neural crest origin. It has been widely accepted that non-coding RNAs (ncRNAs) play important roles in many types of cancer, including glioma and gastrointestinal cancers. They may regulate the cancer gene network. According to recent sequencing and profiling studies, ncRNAs genes are deregulated in human cancers via deletion, amplification, abnormal epigenetic, or transcriptional regulation. Disturbances in the expression of ncRNAs may act either as oncogenes or as anti-tumor suppressor genes, and can lead to the induction of cancer hallmarks. ncRNAs can be secreted from tumor cells inside exosomes, where they can be transferred to other cells to affect their function. However, these topics still need more study to clarify their exact roles, so the present review addresses different roles and functions of ncRNAs in neuroblastoma.

Indexed as

NeuroblastomaRNA, UntranslatedGene Expression RegulationHumansOncogenesRNA, Untranslated

Identifiers

PMID37217790
OpenAlexW4377232127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.