Evidence map›Paper›PMID 37217783›Full record

ReviewPediatric radiology2023

Tuberculosis revisted: classic imaging findings in childhood.

Nasreen Mahomed, Tracy Kilborn, Elsabe Jacoba Smit, Winnie Chiu Wing Chu, Catherine Yee Man Young, Nonceba Koranteng, Joanna Kasznia-Brown, Abbey J Winant, Edward Y Lee, Kushaljit Singh Sodhi

Open access · hybridAbstract readReview
In one paragraph

Review in Pediatric radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Imaging of pediatric pulmonary infections: A pictorial review.World journal of clinical pediatrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 6 countries.

Nasreen MahomedUniversity of Witwatersrand, 7 York Road Parktown, Johannesburg, 2193, South Africa. Nasreen.mahomed@wits.ac.za.ORCID 0000-0003-4442-9872
Tracy KilbornRed Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-1977-3700
Elsabe Jacoba SmitRed Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-6780-2225
Winnie Chiu Wing ChuDepartment of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong.ORCID 0000-0003-4962-4132
Catherine Yee Man YoungDepartment of Imaging & Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Nonceba KorantengUniversity of Witwatersrand, 7 York Road Parktown, Johannesburg, 2193, South Africa.ORCID 0000-0002-5291-9874
Joanna Kasznia-BrownUniversity of Bristol, Musgrove Park Hospital, Taunton, UK.ORCID 0000-0001-9370-6763
Abbey J WinantDepartment of Radiology, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA, USA.
Edward Y LeeDepartment of Radiology, Boston Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA, USA.
Kushaljit Singh SodhiMallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-6419-2468
Boston Children's Hospital · USChinese University of Hong Kong · HKUniversity of Cape Town · ZAUniversity of the Witwatersrand · ZAMusgrove Park Hospital · GBWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) remains one of the major public health threats worldwide, despite improved diagnostic and therapeutic methods. Tuberculosis is one of the main causes of infectious disease in the chest and is associated with substantial morbidity and mortality in paediatric populations, particularly in low- and middle-income countries. Due to the difficulty in obtaining microbiological confirmation of pulmonary TB in children, diagnosis often relies on a combination of clinical and radiological findings. The early diagnosis of central nervous system TB is challenging with presumptive diagnosis heavily reliant on imaging. Brain infection can present as a diffuse exudative basal leptomeningitis or as localised disease (tuberculoma, abscess, cerebritis). Spinal TB may present as radiculomyelitis, spinal tuberculoma or abscess or epidural phlegmon. Musculoskeletal manifestation accounts for 10% of extrapulmonary presentations but is easily overlooked with its insidious clinical course and non-specific imaging findings. Common musculoskeletal manifestations of TB include spondylitis, arthritis and osteomyelitis, while tenosynovitis and bursitis are less common. Abdominal TB presents with a triad of pain, fever and weight loss. Abdominal TB may occur in various forms, as tuberculous lymphadenopathy or peritoneal, gastrointestinal or visceral TB. Chest radiographs should be performed, as approximately 15% to 25% of children with abdominal TB have concomitant pulmonary infection. Urogenital TB is rare in children. This article will review the classic radiological findings in childhood TB in each of the major systems in order of clinical prevalence, namely chest, central nervous system, spine, musculoskeletal, abdomen and genitourinary system.

Indexed as

TuberculomaTuberculosis, Central Nervous SystemTuberculosis, Lymph NodeAbscessChildDiagnostic ImagingHumansAdoloescentChildImagingInfantInfectionRadiologySpina ventosaTuberculosis

Identifiers

PMID37217783
PMCPMC10421797
OpenAlexW4377287574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.