Evidence map›Paper›PMID 37217779›Full record

ArticleNPJ digital medicine2023

Solving the explainable AI conundrum by bridging clinicians' needs and developers' goals.

Nadine Bienefeld, Jens Michael Boss, Rahel Lüthy, Dominique Brodbeck, Jan Azzati, Mirco Blaser, Jan Willms, Emanuela Keller

Abstract read
In one paragraph

Article in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nadine BienefeldDepartment of Management, Technology, and Economics, ETH Zurich, Zürich, Switzerland. n.bienefeld@gmail.com.ORCID http://orcid.org/0000-0003-4200-8695
Jens Michael BossNeurocritical Care Unit, Department of Neurosurgery and Institute of Intensive Care Medicine, Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zürich, Switzerland.ORCID http://orcid.org/0000-0002-8043-0961
Rahel LüthyInstitute for Medical Engineering and Medical Informatics, School of Life Sciences FHNW, Muttenz, Switzerland.ORCID http://orcid.org/0000-0003-0998-8847
Dominique BrodbeckInstitute for Medical Engineering and Medical Informatics, School of Life Sciences FHNW, Muttenz, Switzerland.
Jan AzzatiInstitute for Medical Engineering and Medical Informatics, School of Life Sciences FHNW, Muttenz, Switzerland.
Mirco BlaserInstitute for Medical Engineering and Medical Informatics, School of Life Sciences FHNW, Muttenz, Switzerland.
Jan WillmsNeurocritical Care Unit, Department of Neurosurgery and Institute of Intensive Care Medicine, Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zürich, Switzerland.
Emanuela KellerNeurocritical Care Unit, Department of Neurosurgery and Institute of Intensive Care Medicine, Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zürich, Switzerland.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 187331Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 52441_1
6 · The paper itself

Abstract

Explainable artificial intelligence (XAI) has emerged as a promising solution for addressing the implementation challenges of AI/ML in healthcare. However, little is known about how developers and clinicians interpret XAI and what conflicting goals and requirements they may have. This paper presents the findings of a longitudinal multi-method study involving 112 developers and clinicians co-designing an XAI solution for a clinical decision support system. Our study identifies three key differences between developer and clinician mental models of XAI, including opposing goals (model interpretability vs. clinical plausibility), different sources of truth (data vs. patient), and the role of exploring new vs. exploiting old knowledge. Based on our findings, we propose design solutions that can help address the XAI conundrum in healthcare, including the use of causal inference models, personalized explanations, and ambidexterity between exploration and exploitation mindsets. Our study highlights the importance of considering the perspectives of both developers and clinicians in the design of XAI systems and provides practical recommendations for improving the effectiveness and usability of XAI in healthcare.

Identifiers

PMID37217779
PMCPMC10202353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.