SynthesisArchives of gynecology and obstetrics2024
Uterine arteries pulsatility index by Doppler ultrasound in the prediction of preeclampsia: an updated systematic review and meta-analysis.
Synthesis in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Predictive Value of Uterine Artery Pulsatility Index in Placental Insufficiency Across Gestational Stages in a Single Population.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Prediction of Pregnancy Complications Related to Placental Dysfunction: Protocol for a Prospective Cohort Study (Placental Health Study).JMIR research protocols · 2026Article
- Preeclampsia Screening.Diagnostics (Basel, Switzerland) · 2026Review
- Prediction of adverse neonatal outcomes in pregnancy-induced hypertension using IVIM-DWI-based microstructure, microcirculation, and multisequence MR texture features.Abdominal radiology (New York) · 2026Article
- Development and validation of a predictive model for preeclampsia: a retrospective cohort study.Archives of gynecology and obstetrics · 2025Article
- Prevention of Pre-Eclampsia: Modern Strategies and the Role of Early Screening.Journal of clinical medicine · 2025Review
- Quantifying Molecular Changes in the Preeclamptic Rat Placenta with Targeted Contrast-Enhanced Ultrasound Imaging.Molecular imaging and biology · 2025Article
- Impaired implantation as a major upstream pathway of preeclampsia: a narrative synthesis of mechanistic, epidemiological and biomarker evidence.Frontiers in reproductive health · 2025Review
- Predictive value of urine misfolded protein in preeclampsia in twin pregnancies.Archives of gynecology and obstetrics · 2024Article
- Contributions Regarding the Study of Pulsatility and Resistivity Indices of Uterine Arteries in Term Pregnancies-A Prospective Study in Bucharest, Romania.Diagnostics (Basel, Switzerland) · 2024Article
- Evaluation of outcomes and risk factors for recurrent preeclampsia in a subsequent pregnancy.Archives of gynecology and obstetrics · 2024Article
- A dynamic prediction model for preeclampsia using the sFlt-1/PLGF ratio combined with multiple factors.BMC pregnancy and childbirth · 2024Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreeclampsia is a common pregnancy complication with serious potential risks for maternal and neonatal health. Early prediction of preeclampsia is crucial for timely prevention, surveillance, and treatment to improve maternal and neonatal outcomes. This systematic review aimed to summarize the available evidence on the prediction of preeclampsia based on Doppler ultrasound of uterine arteries at different gestational ages.
methodsA systematic literature search and meta-analysis were conducted to evaluate the sensitivity and specificity of the pulsatility index of Doppler ultrasound of uterine arteries for predicting preeclampsia. The timing of ultrasound scans within and beyond 20 weeks of gestational age was compared to assess its effect on the sensitivity and specificity of the pulsatility index.
resultsThis meta-analysis included 27 studies and 81,673 subjects (3309 preeclampsia patients and 78,364 controls). The pulsatility index had moderate sensitivity (0.586) and high specificity for predicting preeclampsia (0.879) (summary point: sensitivity 0.59; 1-specificity 0.12). Subgroup analysis revealed that ultrasound scans performed within 20 weeks of gestational age did not significantly affect the sensitivity and specificity for predicting preeclampsia. The summary receiver operator characteristic curve showed the pulsatility index's optimal range of sensitivity and specificity.
conclusionsThe uterine arteries pulsatility index measured by Doppler ultrasound is useful and effective for predicting preeclampsia and should be implemented in the clinical practice. The timing of ultrasound scans at different gestational age ranges does not significantly affect the sensitivity and specificity.
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