ArticleCommunications medicine2023
Imaging immunomodulatory treatment responses in a multiple sclerosis mouse model using hyperpolarized
Article in Communications medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 9 citations in OpenAlex.
- HyperpolarizedResearch square · 2026Article
- Feasibility of multimodal metabolic analysis for detecting early changes in acute neuroinflammation.Journal of neuroinflammation · 2026Article
- HyperpolarizedImaging neuroscience (Cambridge, Mass.) · 2026Article
- Cross-modality network phenotyping: a multivariate MRI biomarker signature predicts spatial pathology and clinical severity in EAE.Frontiers in neurology · 2026Article
- Non-invasive visualisation of long-lasting brain metabolic alterations in murine pseudo-infection model using parahydrogen-polarised [1-Discover nano · 2025Article
- Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025Review
- Immunometabolic editing of the tumor microenvironment: from reprogramming mechanisms to therapeutic vulnerabilities.Frontiers in immunology · 2025Review
- [Research Progress in Applying HyperpolarizedSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Review
- New Horizons in HyperpolarizedMolecular imaging and biology · 2024Article
- Investigating the origin of theNMR in biomedicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundIn recent years, the ability of conventional magnetic resonance imaging (MRI), including T
methodsWe studied the combined cuprizone and experimental autoimmune encephalomyelitis (CPZ-EAE) mouse model of MS, which presents inflammatory-mediated demyelinated lesions in the central nervous system as commonly seen in MS patients. Using hyperpolarized
resultsWe show that hyperpolarized [1-
conclusionsIn conclusion, hyperpolarized MRS metabolic imaging of [1-
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.