Evidence map›Paper›PMID 37217502›Full record

ArticleScientific reports2023

DELMEP: a deep learning algorithm for automated annotation of motor evoked potential latencies.

Diego Milardovich, Victor H Souza, Ivan Zubarev, Sergei Tugin, Jaakko O Nieminen, Claudia Bigoni, Friedhelm C Hummel, Juuso T Korhonen, Dogu B Aydogan, Pantelis Lioumis and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Diego Milardovich *Institute for Microelectronics, Technische Universität Wien, Gußhausstraße 27-29/E360, 1040, Vienna, Austria. milardovich@iue.tuwien.ac.at.ORCID 0000-0003-2453-1693
Victor H Souza *Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0002-0254-4322
Ivan ZubarevDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0002-1620-8485
Sergei TuginDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0002-1274-8863
Jaakko O NieminenDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0002-7826-3519
Claudia BigoniDefitech Chair of Clinical Neuroengineering, Neuro-X Institute (INX) and Brain Mind Institute (BMI), École Polytechnique Fédérale de Lausanne (EPFL), 1202, Geneva, Switzerland.ORCID 0000-0002-5142-5434
Friedhelm C HummelDefitech Chair of Clinical Neuroengineering, Neuro-X Institute (INX) and Brain Mind Institute (BMI), École Polytechnique Fédérale de Lausanne (EPFL), 1202, Geneva, Switzerland.ORCID 0000-0002-4746-4633
Juuso T KorhonenDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0001-7802-7084
Dogu B AydoganDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0002-7840-3294
Pantelis LioumisDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0003-2016-9199
Nima TaherinejadInstitute for Computer Technology, Technische Universität Wien, Vienna, Austria.ORCID 0000-0002-1295-0332
Tibor GrasserInstitute for Microelectronics, Technische Universität Wien, Gußhausstraße 27-29/E360, 1040, Vienna, Austria.ORCID 0000-0001-6536-2238
Risto J IlmoniemiDepartment of Neuroscience and Biomedical Engineering, Aalto University School of Science, Espoo, Finland.ORCID 0000-0002-3340-2618

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The analysis of motor evoked potentials (MEPs) generated by transcranial magnetic stimulation (TMS) is crucial in research and clinical medical practice. MEPs are characterized by their latency and the treatment of a single patient may require the characterization of thousands of MEPs. Given the difficulty of developing reliable and accurate algorithms, currently the assessment of MEPs is performed with visual inspection and manual annotation by a medical expert; making it a time-consuming, inaccurate, and error-prone process. In this study, we developed DELMEP, a deep learning-based algorithm to automate the estimation of MEP latency. Our algorithm resulted in a mean absolute error of about 0.5 ms and an accuracy that was practically independent of the MEP amplitude. The low computational cost of the DELMEP algorithm allows employing it in on-the-fly characterization of MEPs for brain-state-dependent and closed-loop brain stimulation protocols. Moreover, its learning ability makes it a particularly promising option for artificial-intelligence-based personalized clinical applications.

Indexed as

Deep LearningMotor CortexAlgorithmsElectromyographyEvoked Potentials, MotorTranscranial Magnetic Stimulation

Identifiers

PMID37217502
PMCPMC10203150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.