ArticleNature communications2023
Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
- Algae-specific immune modulation influences responses to heat and pathogen challenge in a symbiotic coral.Science advances · 2026Article
- Restoration stocks of a caribbean coral species contain low levels of inherent stony coral tissue loss disease resistance.Scientific reports · 2026Article
- Frequent coral disease interventions reduces tissue loss.Scientific reports · 2026Article
- Runaway coral-algal dysbiosis may be responsible for rapid coral tissue loss.Scientific reports · 2026Article
- Article
- Key coral symbiont lineages (family Symbiodiniaceae) are differentially associated with stony coral tissue loss disease.ISME communications · 2026Article
- Genotype and symbiont composition rather than environment influence susceptibility to stony coral tissue loss disease in coral restoration broodstock.Scientific reports · 2025Article
- Machine learning reveals distinct gene expression signatures across tissue states in stony coral tissue loss disease.Royal Society open science · 2025Article
- Shifts in the microbiome and virome are associated with stony coral tissue loss disease (SCTLD).ISME communications · 2025Article
- Caribbean fish feces are an environmental hotspot of viable Symbiodiniaceae.Frontiers in microbiology · 2025Article
- Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation.mSystems · 2024Article
- Structural and Evolutionary Relationships of Melanin Cascade Proteins in Cnidarian Innate Immunity.Integrative and comparative biology · 2024Article
- Trade-off between photosymbiosis and innate immunity influences cnidarian's response to pathogenic bacteria.Proceedings. Biological sciences · 2024Article
- Novel metagenomics analysis of stony coral tissue loss disease.G3 (Bethesda, Md.) · 2024Article
- The coral microbiome in sickness, in health and in a changing world.Nature reviews. Microbiology · 2024Review
- Novel metagenomics analysis of stony coral tissue loss disease.bioRxiv : the preprint server for biology · 2024Article
- Stony coral tissue loss disease indirectly alters reef communities.Science advances · 2024Article
- Global warming-related response after bacterial challenge in Astroides calycularis, a Mediterranean thermophilic coral.Scientific reports · 2024Article
- Annotated genome and transcriptome of the endangered Caribbean mountainous star coral (Orbicella faveolata) using PacBio long-read sequencing.BMC genomics · 2024Article
- Microbiomes of three coral species in the Mexican Caribbean and their shifts associated with the Stony Coral Tissue Loss Disease.PloS one · 2024Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral diseases on record, affects over 22 species of reef-building coral and is decimating reefs throughout the Caribbean. To understand how different coral species and their algal symbionts (family Symbiodiniaceae) respond to this disease, we examine the gene expression profiles of colonies of five species of coral from a SCTLD transmission experiment. The included species vary in their purported susceptibilities to SCTLD, and we use this to inform gene expression analyses of both the coral animal and their Symbiodiniaceae. We identify orthologous coral genes exhibiting lineage-specific differences in expression that correlate to disease susceptibility, as well as genes that are differentially expressed in all coral species in response to SCTLD infection. We find that SCTLD infection induces increased expression of rab7, an established marker of in situ degradation of dysfunctional Symbiodiniaceae, in all coral species accompanied by genus-level shifts in Symbiodiniaceae photosystem and metabolism gene expression. Overall, our results indicate that SCTLD infection induces symbiophagy across coral species and that the severity of disease is influenced by Symbiodiniaceae identity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.