ArticleJournal of clinical epidemiology2023
Scoping review of measures of treatment burden in patients with multimorbidity: advancements and current gaps.
Article in Journal of clinical epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Reclaiming time as a fundamental determinant of health equity.SSM - population health · 2026Article
- Time toxicity in chronic disease comorbidity care: A concept analysis using Walker and Avant's approach.International journal of nursing sciences · 2026Article
- Assessing Older Adults' Adherence to Appropriate Polypharmacy: Selection of Outcome Measures for Intervention Trials.Journal of the American Geriatrics Society · 2026Article
- The Treatment Burden for Multimorbidity Scale: A Development and Psychometric Validation Study.Nursing & health sciences · 2026Article
- Physician Characteristics Associated with Prioritizing Treatment Burden in Outpatient Care for Older Adults with Multimorbidity.JMA journal · 2026Article
- WHF Roadmap for Integrated Care in People Living with - or at Risk of - Cardiovascular Disease and Multiple Long-Term Conditions.Global heart · 2026Review
- Disparities in treatment burden in Peru among people with multiple long-term conditions by geography and healthcare facility: A cross-sectional study.PLOS global public health · 2026Article
- Workload-capacity imbalances and their impact on self-management complexity in patients with multimorbidity: a multicenter cross-sectional study.Annals of medicine · 2025Article
- The relationship between social support, psychological distress, and patient activation in peritoneal dialysis patients: a cross-sectional study.BMC nephrology · 2025Article
- Development and validation of a Japanese version of the multimorbidity treatment burden questionnaire.Scientific reports · 2025Article
- Increasing Life Expectancy in Patients with Genitourinary Malignancies: Impact of Treatment Burden on Disease Management and Quality of Life.European urology · 2025Review
- Patient experience of treatment burden in chronic heart failure self-care interventions: a qualitative systematic review protocol.BMJ open · 2025Article
- A Pathway Analysis of Factors Affecting Quality of Life in Peritoneal Dialysis Patients: A Cross-Sectional Study Based on Individual and Family Self-Management Theory.Patient preference and adherence · 2025Article
- Burden of Treatment in Children and Adolescents With Type 1 Diabetes Evaluated by Focus Groups.Pediatric diabetes · 2025Article
- Measurement of treatment burden in patients with multimorbidity in the Netherlands: translation and validation of the Multimorbidity Treatment Burden Questionnaire (NL-MTBQ).Family practice · 2024Article
- The Arabic medication-related burden quality of life (MRB-QoL) tool: Cross-cultural adaptation and content validation.Exploratory research in clinical and social pharmacy · 2024Article
- Treatment burden in multimorbidity: an integrative review.BMC primary care · 2024Review
- Regular source of primary care and health services utilisation among Brazilian elderly with mental-physical multimorbidity.BMC geriatrics · 2024Article
- Development of the Short Treatment Burden Questionnaire (STBQ) including a Global Treatment Burden Question (GTBQ): Cognitive interviews with adults living with multimorbidity.Journal of multimorbidity and comorbidityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
Abstract
objectivesTo identify, assess, and summarize the measures to assess burden of treatment in patients with multimorbidity (BoT-MMs) and their measurement properties. STUDY DESIGN AND
settingMEDLINE via PubMed was searched from inception until May 2021. Independent reviewers extracted data from studies in which BoT-MMs were developed, validated, or reported as used, including an assessment of their measurement properties (e.g., validity and reliability) using the COnsensus-based Standards for the selection of health Measurement INstruments.
resultsEight BoT-MMs were identified across 72 studies. Most studies were performed in English (68%), in high-income countries (90%), without noting urban-rural settings (90%). No BoT-MMs had both sufficient content validity and internal consistency; some measurement properties were either insufficient or uncertain (e.g., responsiveness). Other frequent limitations of BoT-MMs included absent recall time, presence of floor effects, and unclear rationale for categorizing and interpreting raw scores.
conclusionThe evidence needed for use of extant BoT-MMs in patients with multimorbidity remains insufficiently developed, including that of suitability for their development, measurement properties, interpretability of scores, and use in low-resource settings. This review summarizes this evidence and identifies issues needing attention for using BoT-MMs in research and clinical practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.