Evidence map›Paper›PMID 37217104›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2023

Metabolism and pharmacokinetics of vitamin D in patients with cystic fibrosis.

Mackenzie C Bergagnini-Kolev, Simon Hsu, Moira L Aitken, Christopher H Goss, Andrew N Hoofnagle, Leila R Zelnick, Dawn Lum, Cora M Best, Kenneth E Thummel, Bryan R Kestenbaum and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Cystic fibrosis-related bone disease: an update on screening, diagnosis, and treatment.Therapeutic advances in endocrinology and metabolism · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mackenzie C Bergagnini-KolevDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.
Simon HsuKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Division of Nephrology, Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address: sihsu@uw.edu.
Moira L AitkenDivision of Pulmonary, Critical Care and Sleep Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Christopher H GossDepartment of Pediatrics, School of Medicine, University of Washington, Seattle, WA 98195, USA; Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Andrew N HoofnagleKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Department of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Leila R ZelnickKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Division of Nephrology, Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Dawn LumKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Division of Nephrology, Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Cora M BestKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Department of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Kenneth E ThummelDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.
Bryan R KestenbaumKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Division of Nephrology, Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Ian H de BoerKidney Research Institute, University of Washington, Seattle, WA 98104, USA; Division of Nephrology, Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA.
Yvonne S LinDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195, USA.
University of Washington · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
PILOT STUDY--CLINICAL NUTRITION RESEARCHP30DK035816 · NIDDK · UNIVERSITY OF WASHINGTON · PI Ellen A Schur · 1986 to 2026
$30.4M
Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss · 2010 to 2026
$21.4M
Pharmacological Sciences SupplementT32GM007750 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 1985 to 2023
$12.6M
Nutrition, Obesity and Atherosclerosis Training ProgramT32HL007028 · NHLBI · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1985 to 2026
$6.4M
RESEARCH TRAINING IN RENAL DISEASET32DK007467 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA, KESTENBAUM, BRYAN R · 1986 to 2023
$5.1M
Vitamin D Catabolism in Chronic Kidney DiseaseR01DK099199 · NIDDK · UNIVERSITY OF WASHINGTON · PI DE BOER, IAN H · 2014 to 2018
$3.2M
NHLBI NIH HHS T32 HL007028NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30 DK035816NIDDK NIH HHS P30 DK089507NIDDK NIH HHS R01 DK099199NIDDK NIH HHS T32 DK007467NIGMS NIH HHS T32 GM007750
6 · The paper itself

Abstract

Patients with cystic fibrosis (CF) commonly have lower circulating concentrations of 25-hydroxyvitamin D (25(OH)D) than healthy populations. We comprehensively compared measures of vitamin D metabolism among individuals with CF and healthy control subjects. In a cross-sectional study, serum from participants with CF (N = 83) and frequency-matched healthy control subjects by age and race (N = 82) were analyzed for: 25(OH)D

Indexed as

Cystic Fibrosis24,25-Dihydroxyvitamin D 3CalcifediolCross-Sectional StudiesHumansProspective StudiesVitamin DVitamins24,25-Dihydroxyvitamin D 3CalcifediolVitamin DVitamins1α,25-dihydroxyvitamin D24,25-dihydroxyvitamin D25-hydroxyvitamin DCystic fibrosisPharmacokinetics

Identifiers

PMID37217104
PMCPMC10524963
OpenAlexW4377141657

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.