Evidence map›Paper›PMID 37216796›Full record

ArticlePlacenta2023

Associations of prenatal exposure to NO

Michael R Hussey, Daniel A Enquobahrie, Christine T Loftus, James W MacDonald, Theo K Bammler, Alison G Paquette, Carmen J Marsit, Adam A Szpiro, Joel D Kaufman, Kaja Z LeWinn and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Placenta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Michael R HusseyDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA. Electronic address: husseymi@uw.edu.
Daniel A EnquobahrieDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA; Department of Health Systems and Population Health, School of Public Health, University of Washington, Seattle, WA, USA.
Christine T LoftusDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.
James W MacDonaldDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.
Theo K BammlerDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.
Alison G PaquetteDepartment of Pediatrics, School of Medicine, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA.
Carmen J MarsitGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Adam A SzpiroDepartment of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA.
Joel D KaufmanDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA; Department of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.
Kaja Z LeWinnDepartment of Psychiatry and Behavioral Sciences, School of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Nicole R BushDepartment of Psychiatry and Behavioral Sciences, School of Medicine, University of California, San Francisco, San Francisco, CA, USA; Department of Pediatrics, School of Medicine, University of California, San Francisco, San, Francisco, CA, USA.
Frances TylavskyDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Qi ZhaoDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Catherine J KarrDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA; Department of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA; Department of Pediatrics, School of Medicine, University of Washington, Seattle, WA, USA.
Sheela SathyanarayanaDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA; Department of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA; Department of Pediatrics, School of Medicine, University of Washington, Seattle, WA, USA; Seattle Children's Research Institute, Seattle, WA, USA.
University of Washington · USUniversity of California, San Francisco · USUniversity of Tennessee Health Science Center · USEmory University · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Urban Air Pollution and Pathological Brain Aging: A Nationwide Twin Study in MenP01AG055367 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2018 to 2022
$11.5M
Biostatistics, Epidemiologic & Bioinformatic Training in Environmental HealthT32ES015459 · NIEHS · UNIVERSITY OF WASHINGTON · PI June T. Spector · 2009 to 2026
$10.6M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUG3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2016 to 2017
$5.1M
SPIROMICS - Air Pollution StudyR01ES023500 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N, KAUFMAN, JOEL DANIEL · 2014 to 2018
$3.2M
Environmental Determinants of Pathological Brain Aging in WHI Memory StudiesR01ES025888 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JIU-CHIUAN, KAUFMAN, JOEL DANIEL · 2016 to 2020
$3.2M
The Role of Corticotrophin Releasing Hormone on Placental Transcriptional Networks and Birth TimingR00HD096112 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PAQUETTE, ALISON GENEVIEVE · 2020 to 2022
$721k
Air Pollution, Heart Failure and Atrial Fibrillation in MESAR56ES026528 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAUFMAN, JOEL DANIEL · 2017 to 2017
$601k
The role of Corticotrophin Releasing Hormone on placental transcriptional networks and birth timingK99HD096112 · NICHD · INSTITUTE FOR SYSTEMS BIOLOGY · PI PAQUETTE, ALISON GENEVIEVE · 2018 to 2019
$258k
EPA RD838300NIA NIH HHS P01 AG055367NICHD NIH HHS K99 HD096112NICHD NIH HHS R00 HD096112NIEHS NIH HHS P30 ES007033NIEHS NIH HHS R01 ES023500NIEHS NIH HHS R01 ES025888NIEHS NIH HHS R56 ES026528NIEHS NIH HHS T32 ES015459NIH HHS UG3 OD023271NIH HHS UH3 OD023271
6 · The paper itself

Abstract

introductionTraffic-related air pollution (TRAP), a common exposure, potentially impacts pregnancy through altered placental function. We investigated associations between prenatal TRAP exposure and placental gene expression.

methodsWhole transcriptome sequencing was performed on placental samples from CANDLE (Memphis, TN) (n = 776) and GAPPS (Seattle and Yakima, WA) (n = 205), cohorts of the ECHO-PATHWAYS Consortium. Residential NO

resultsIn GAPPS, final-month NO DISCUSSION: Overall, pregnancy NO

Indexed as

Air PollutantsPrenatal Exposure Delayed EffectsFemaleGene ExpressionHumansMaleMaternal ExposureNitrogen DioxidePlacentaPregnancyAir PollutantsNitrogen DioxideGene expressionNear-roadway distanceNO(2)PlacentaPregnancyTraffic-related air pollution

Identifiers

PMID37216796
PMCPMC10349584
OpenAlexW4376619934

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.