Evidence map›Paper›PMID 37216765›Full record

ArticleJournal of thermal biology2023

Mediobasal hypothalamic neurons contribute to the control of brown adipose tissue sympathetic nerve activity and cutaneous vasoconstriction.

Clarissa M D Mota, Christopher J Madden

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thermal biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Improving incretin-mediated body weight loss via energy expenditure.Trends in endocrinology and metabolism: TEM · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Clarissa M D MotaDepartment of Neurological Surgery, Oregon Health and Science University, Portland, OR, USA.
Christopher J MaddenDepartment of Neurological Surgery, Oregon Health and Science University, Portland, OR, USA. Electronic address: maddench@ohsu.edu.
Oregon Health & Science University · US

Funding

Neural mechanisms in high fat diet impairment of brown adipose tissue activityR01DK112198 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI MADDEN, CHRISTOPHER J · 2018 to 2022
$2.1M
NIDDK NIH HHS R01 DK112198
6 · The paper itself

Abstract

The mediobasal hypothalamus (MBH) contains heterogeneous neuronal populations that regulate food intake and energy expenditure. However, the role of MBH neurons in the neural control of thermoeffector activity for thermoregulation is not known. This study sought to determine the effects of modulating the activity of MBH neurons on the sympathetic outflow to brown adipose tissue (BAT), BAT thermogenesis, and cutaneous vasomotion. Pharmacological inhibition of MBH neurons by local administration of muscimol, a GABA

Indexed as

Adipose Tissue, BrownCarbon DioxideAnimalsgamma-Aminobutyric AcidNeuronsRatsRats, Sprague-DawleyThermogenesisVasoconstrictionCarbon Dioxidegamma-Aminobutyric AcidArcuate nucleusCold defenseSympathetic nervous systemThermogenesisThermoregulationVentromedial hypothalamus

Identifiers

PMID37216765
PMCPMC10330581
OpenAlexW4376125998

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.