Evidence map›Paper›PMID 37216758›Full record

ReviewThe International journal on drug policy2023

Treatment of opioid use disorder in Ukraine during the first year of the Russia-Ukraine war: Lessons learned from the crisis.

Olga Morozova, Iryna Ivanchuk, Olga Gvozdetska, Olena Nesterova, Pavlo Skala, Ihor Kuzin, Kostyantyn Dumchev

Abstract readReview
In one paragraph

Review in The International journal on drug policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olga MorozovaDepartment of Public Health Sciences, Biological Sciences Division, University of Chicago, Chicago, IL, United States. Electronic address: omorozova@uchicago.edu.
Iryna IvanchukPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.
Olga GvozdetskaPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.
Olena NesterovaPublic Health Center of the Ministry of Health of Ukraine, Kyiv, Ukraine.
Pavlo SkalaInternational Charitable Foundation "Alliance for Public Health", Kyiv, Ukraine.
Ihor KuzinMinistry of Health of Ukraine, Kyiv, Ukraine.
Kostyantyn DumchevUkrainian Institute on Public Health Policy, Kyiv, Ukraine.

Funding

Ukraine HIV Research Training ProgramD43TW010562 · FIC · SUNY DOWNSTATE MEDICAL CENTER · PI DEHOVITZ, JACK A · 2017 to 2021
$1.7M
Ukraine HIV Research Training Program/Aging SupplementD43TW012491 · FIC · SUNY DOWNSTATE MEDICAL CENTER · PI Jack A DeHovitz, Tetiana Kiriazova · 2023 to 2026
$1.0M
FIC NIH HHS D43 TW010562FIC NIH HHS D43 TW012491
6 · The paper itself

Abstract

The Russian invasion of Ukraine in February 2022 caused major disruptions of societal functions, including health care. Patients receiving medications for opioid use disorder (MOUD) depend on receiving daily treatment and face a risk of withdrawal in case of medication supply disruption. MOUD are banned in Russia, making treatment continuation impossible in temporarily occupied areas. In this paper, we review the situation with MOUD delivery in Ukraine during the first year of the Russia-Ukraine war. Legislative changes and mobilization of efforts in the time of crisis ensured treatment continuation for thousands of patients. In areas controlled by Ukraine, most patients were receiving take-home doses for up to 30 days, some experienced temporary dosing reductions. Programs in temporarily occupied regions were shut down likely leading to abrupt withdrawal among many patients. At least 10% of patients have been internally displaced. One year into the war, the number of MOUD patients in governmental clinics of Ukraine increased by 17%, and the data suggest that the coverage of private clinics has also increased. But the risks for program stability remain high as the current medication supply relies on one manufacturing facility. Using lessons learned from the crisis, we provide recommendations for future response to minimize the risks of major adverse outcomes among patients treated for opioid use disorder.

Indexed as

BuprenorphineOpioid-Related DisordersAnalgesics, OpioidAntisocial Personality DisorderGovernmentHumansOpiate Substitution TreatmentRussiaUkraineAnalgesics, OpioidBuprenorphineDisplacementMedications for opioid use disorderMethadoneOpioid use disorderUkraineWar

Identifiers

PMID37216758
PMCPMC11328943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.