Evidence map›Paper›PMID 37216542›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Osteolectin increases bone elongation and body length by promoting growth plate chondrocyte proliferation.

Jingzhu Zhang, Liming Du, Bethany Davis, Zhimin Gu, Junhua Lyu, Zhiyu Zhao, Jian Xu, Sean J Morrison

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Bone matrix proteins: regulators of skeletal remodeling and repair.Journal of bone and mineral metabolism · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jingzhu ZhangChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0001-8811-1319
Liming DuChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Bethany DavisChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Zhimin GuChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Junhua LyuChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Zhiyu ZhaoChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Jian XuChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0003-1988-7337
Sean J MorrisonChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.ORCID 0000-0003-1587-8329
The University of Texas Southwestern Medical Center · US

Funding

Molecular Analysis of Transcriptional Enhancers in HematopoiesisR01DK111430 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jian Xu · 2016 to 2026
$4.8M
Elucidating the Functional and Mechanistic Roles of LINE-1 Retrotransposons in Myeloid LeukemiaR01CA259581 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Jian Xu · 2022 to 2026
$2.3M
NCI NIH HHS R01 CA259581NIDDK NIH HHS R01 DK111430
6 · The paper itself

Abstract

Osteolectin is a recently identified osteogenic growth factor that binds to Integrin α11 (encoded by

Indexed as

ChondrocytesOsteogenesisAdultAnimalsBone and BonesCell DifferentiationCell ProliferationGenome-Wide Association StudyGrowth PlateHumansIntegrinsMiceIntegrinsbone elongationchondrocyteintegrin α11osteogenesisosteolectin

Identifiers

PMID37216542
PMCPMC10235998
OpenAlexW4377289032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.