Evidence map›Paper›PMID 37216142›Full record

ArticleJournal of translational autoimmunity2023

Antiphospholipid antibodies induce proinflammatory and procoagulant pathways in endothelial cells.

Markos Patsouras, Eirini Alexopoulou, Spyros Foutadakis, Eirini Tsiki, Panagiota Karagianni, Marios Agelopoulos, Panayiotis G Vlachoyiannopoulos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational autoimmunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Markos PatsourasDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece.
Eirini AlexopoulouDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece.
Spyros FoutadakisCenter of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou Street, Athens, 11527, Greece.
Eirini TsikiDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece.
Panagiota KaragianniDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece.
Marios AgelopoulosCenter of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou Street, Athens, 11527, Greece.
Panayiotis G VlachoyiannopoulosDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece.
National and Kapodistrian University of Athens · GRAcademy of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia characterized by recurrent thrombotic events and/or pregnancy morbidity in the presence of antiphospholipid antibodies detected either as anti-cardiolipin, anti-β2 Glycoprotein I (anti-β2GPI) or Lupus anticoagulant (LA). Endothelial deregulation characterizes the syndrome. To address gene expression changes accompanying the development of autoimmune phenotype in endothelial cells in the context of APS, we performed

Indexed as

Antiphospholipid syndrome (APS)Computational biology toolsGene expression programsInflammatory and procoagulant phenotypeTranscriptional regulatorsTranscriptomics analysis

Identifiers

PMID37216142
PMCPMC10197110
OpenAlexW4367692892

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.