Profiling of phosphorylated metabolites from lung cancer by zeolite loaded Mg-Al-Ce ternary hydroxide (Zeolite@MAC) composite.

Rimsha Batool, Batool Fatima, Fahmida Jabeen, Dilshad Hussain, Muhammad Imran, Muhammad Najam-Ul-Haq

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Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Rimsha BatoolDepartment of Biochemistry, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Batool FatimaDepartment of Biochemistry, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Fahmida JabeenInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Dilshad HussainHEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.

Muhammad ImranBiochemistry Section, Institute of Chemical Sciences, University of Peshawar, 25120, Pakistan.

Muhammad Najam-Ul-HaqInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorylated metabolites are linked to metabolism, and the dysregulation of metabolic reactions brings cancer. Dysregulated levels lead to hyperactivation of glycolytic and mitochondrial oxidative phosphorylation pathways. Abnormal concentrations are the indicators of energy-related disorders. In this work, Zeolite-loaded Mg-Al-Ce hydroxides (Zeolite@MAC) are prepared by co-precipitation and characterized through FTIR, XRD, SEM, BET, AFM, TEM, and DLS. Magnesium-Aluminum-Cerium-Zeolite particles enrich phosphate-containing small molecules. These ternary hydroxides carried out the main adsorption mechanism, which swapped the surface hydroxyl group ligands for phosphate and the inner-sphere complex of CePO

Indexed as

BiomarkersCeria nanoparticlesMetabolitesPhosphorylated biomoleculesZeolite

Identifiers

PMID37215921

DOI10.1016/j.heliyon.2023.e16098

PMCPMC10196856

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