SynthesisFrontiers in psychiatry2023
Personality traits as risk factors for relapse or recurrence in major depression: a systematic review.
Synthesis in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Harnessing digital health interventions to address the heterogeneity of depression: a systematic review.Frontiers in digital health · 2025Pooled it
- Neuroticism as a Common Factor in Depression and Anxiety Associated with Multiple Sclerosis-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2024Pooled it
- Long-term dosage effects of psychodynamic and schema therapy in depressed patients with personality disorders: 18 and 24 months follow-up of a randomized controlled trial.Psychological medicine · 2025Trial
- Delay discounting correlates with depression but does not predict relapse after antidepressant discontinuation.Molecular psychiatry · 2026Article
- Association between biological rhythm disruption and suicidal ideation in patients with major depressive disorder: a chain mediation of neuroticism and emotion regulation difficulties.Frontiers in psychiatry · 2026Article
- The significance of personality disorder and traits in short-term psychodynamic and cognitive behavioral therapy for major depression.Frontiers in psychiatry · 2026Article
- Prevalence and Correlates of Depression and Suicidal Ideation Across Stages 0-4 of Cardiovascular-Kidney-Metabolic Syndrome.Brain and behavior · 2025Article
- Psychopathological Correlates of Dysfunctional Smartphone and Social Media Use: The Role of Personality Disorders in Technological Addiction and Digital Life Balance.European journal of investigation in health, psychology and education · 2025Article
- Patients' anesthesia preferences for Cesarean delivery: exploring the role of personality beliefs in spinal vs. General anesthesia.BMC anesthesiology · 2025Observational
- Personality perspective on depression and anxiety symptoms among Chinese adolescents and young adults: a two-sample network analysis.BMC psychiatry · 2025Article
- The impact of personality traits on the return of major depression: a case-control study.Frontiers in psychology · 2025Article
- The Path from Personality to Anxiety and Depression Is Mediated by Cognition in Multiple Sclerosis.Journal of personalized medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Major depressive disorder (MDD) is highly recurrent. Identifying risk factors for relapse in depression is essential to improve prevention plans and therapeutic outcomes. Personality traits and personality disorders are widely considered to impact outcomes in MDD. We aimed to evaluate the role of personality aspects in the risk of relapse and recurrence in MDD. Method: A PROSPERO-registered systematic review was conducted using Medline, Embase, PsycINFO, Web of Science and CINAHL as data sources, together with hand searching of four journals over the five years till 2022. There was independent abstract selection, quality assessment and data extraction from each study. Results: Twenty two studies me t eligibility criteria involving 12,393 participants. Neurotic personality features are significantly associated with the risk of relapse and recurrence of depression, though the data is not uniform. There is some, though limited, evidence that borderline, obsessive-compulsive and dependent personality traits or disorders increase the risk for relapse in depression. Limitations: The small number, in addition to the methodological heterogeneity of the included studies, did not allow further analysis, such as meta-analysis. Conclusion: People with high neuroticism and dependent personality traits, borderline personality disorder or obsessive-compulsive personality disorder, compared to those without, may be at a higher risk of experiencing relapse or recurrence of MDD. Specific and targeted interventions may potentially reduce relapse and recurrence rates in these groups and could improve outcomes. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=235919, identifier: CRD42021235919.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.