Evidence map›Paper›PMID 37215633›Full record

ArticlePNAS nexus2023

Multiplexed neuropeptide mapping in ant brains integrating microtomography and three-dimensional mass spectrometry imaging.

Benedikt Geier, Esther Gil-Mansilla, Zita Liutkevičiūtė, Roland Hellinger, Jozef Vanden Broeck, Janina Oetjen, Manuel Liebeke, Christian W Gruber

Open access · goldAbstract read
In one paragraph

Article in PNAS nexus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Benedikt GeierDepartment of Symbiosis, Max Planck Institute for Marine Microbiology, Bremen 28359, Germany.ORCID https://orcid.org/0000-0002-2942-2624
Esther Gil-MansillaCenter for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria.
Zita LiutkevičiūtėCenter for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria.
Roland HellingerCenter for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria.
Jozef Vanden BroeckMolecular Developmental Physiology and Signal Transduction Group, Zoological Institute, KU Leuven, Leuven 3000, Belgium.ORCID https://orcid.org/0000-0001-7653-0516
Janina OetjenBruker Daltonics GmbH & Co. KG, Life Science Mass Spectrometry, Bremen 28359, Germany.ORCID https://orcid.org/0000-0002-4088-5742
Manuel LiebekeDepartment of Symbiosis, Max Planck Institute for Marine Microbiology, Bremen 28359, Germany.ORCID https://orcid.org/0000-0002-2339-1409
Christian W GruberCenter for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria.ORCID https://orcid.org/0000-0001-6060-7048
Medical University of Vienna · ATChristian-Albrechts-Universität zu Kiel · DEMax Planck Institute for Marine Microbiology · DEUniversity of Bremen · DEZoological Institute · RU

Funding

Austrian Science Fund FWF I 3243Austrian Science Fund FWF P 32109
6 · The paper itself

Abstract

Neuropeptides are important regulators of animal physiology and behavior. Hitherto the gold standard for the localization of neuropeptides have been immunohistochemical methods that require the synthesis of antibody panels, while another limiting factor has been the brain's opacity for subsequent in situ light or fluorescence microscopy. To address these limitations, we explored the integration of high-resolution mass spectrometry imaging (MSI) with microtomography for a multiplexed mapping of neuropeptides in two evolutionary distant ant species,

Identifiers

PMID37215633
PMCPMC10194420
OpenAlexW4366985813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.