Evidence map›Paper›PMID 37215628›Full record

ArticleBuilding and environment2022

Spring is associated with increased total and allergenic fungal concentrations in house dust from a pediatric asthma cohort in New York City.

Samuel J Cochran, Luis Acosta, Adnan Divjan, Angela R Lemons, Andrew G Rundle, Rachel L Miller, Edward Sobek, Brett J Green, Matthew S Perzanowski, Karen C Dannemiller

Open access · greenAbstract read
In one paragraph

Article in Building and environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. The Indoor Microbiome: Sampling, Analysis and Emerging Trends.Environmental microbiology reports · 2026
    Pooled it
  2. Article
  3. Article
  4. Mold exposure and rhinitis symptoms among children attending Head Start centers in New York City.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.The Journal of allergy and clinical immunology · 2025
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Samuel J CochranDepartment of Civil, Environmental and Geodetic Engineering, College of Engineering, Ohio State University, Columbus, OH, 43210, USA.
Luis AcostaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA.
Adnan DivjanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA.
Angela R LemonsHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, 26505, USA.
Andrew G RundleDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, 10032, NY, USA.
Rachel L MillerDivision of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Edward SobekAssured Bio Laboratories, Oak Ridge, TN, 37830, USA.
Brett J GreenHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, 26505, USA.
Matthew S PerzanowskiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA.
Karen C DannemillerDepartment of Civil, Environmental and Geodetic Engineering, College of Engineering, Ohio State University, Columbus, OH, 43210, USA.
Columbia University · USCenters for Disease Control and Prevention · USThe Ohio State University · USAssured Bio (United States) · USIcahn School of Medicine at Mount Sinai · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Risk Factors Accounting for Neighborhood Differences in Asthma PrevalenceR01ES014400 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PERZANOWSKI, MATTHEW S · 2007 to 2010
$2.9M
Intramural CDC HHS CC999999NCI NIH HHS P30 CA016058NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES014400
6 · The paper itself

Abstract

Introduction: Asthma and allergy symptoms vary seasonally due to exposure to environmental sources of allergen, including fungi. However, we need an improved understanding of seasonal influence on fungal exposures in the indoor environment. We hypothesized that concentrations of total fungi and allergenic species in vacuumed dust vary significantly by season. Objective: Assess seasonal variation of indoor fungi with greater implications related to seasonal asthma control. Methods: We combined next-generation sequencing with quantitative polymerase chain reaction (qPCR) to measure concentrations of fungal DNA in indoor floor dust samples (n = 298) collected from homes participating in the New York City Neighborhood Asthma and Allergy Study (NAAS). Results: Total fungal concentration in spring was significantly higher than the other three seasons (p ≤ 0.005). Mean concentrations for 78% of fungal species were elevated in the spring (26% were significantly highest in spring, p < 0.05). Concentrations of 8 allergenic fungal species were significantly (p < 0.5) higher in spring compared to at least two other seasons. Indoor relative humidity and temperature were significantly highest in spring (p < 0.05) and were associated with total fungal concentration (R Conclusion: There is significant seasonal variation in total fungal concentration and concentration of select allergenic species. Indoor relative humidity and temperature may underlie these associations.

Indexed as

AsthmaDustFungiIndoorqPCRSpring

Identifiers

PMID37215628
PMCPMC10193533
OpenAlexW4306407411

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.