ArticleNeurobiology of language (Cambridge, Mass.)2022
The Precentral Gyrus Contributions to the Early Time-Course of Grapheme-to-Phoneme Conversion.
Article in Neurobiology of language (Cambridge, Mass.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Non-verbal dichotic listening: A new cognitive hearing test for dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Speech sequencing in the human precentral gyrus.Nature human behaviour · 2025Article
- From retinotopic to ordinal coding: Dissecting the cortical stages of visual word recognition.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Implications of shared motor and perceptual activations on the sensorimotor cortex for neuroprosthetic decoding.Journal of neural engineering · 2025Article
- Misspelled-Word Reading Modulates Late Cortical Dynamics.Human brain mapping · 2025Article
- Separating feedforward and feedback dynamics using time-frequency resolved connectivity: A hybrid model of left ventral occipitotemporal cortex in word reading.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Visual word processing engages a hierarchical, distributed, and bilateral cortical network.iScience · 2024Article
- Cortical Structure in Pre-Readers at Cognitive Risk for Dyslexia: Baseline Differences and Response to Intervention.Neurobiology of language (Cambridge, Mass.) · 2024Article
- A Neurosurgical Functional Dissection of the Middle Precentral Gyrus during Speech Production.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
- The Angular Gyrus as a Hub for Modulation of Language-related Cortex by Distinct Prefrontal Executive Control Regions.Journal of cognitive neuroscience · 2022Article
- A Spatiotemporal Map of Reading Aloud.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Functional Connectome Dynamics After Mild Traumatic Brain Injury According to Age and Sex.Frontiers in aging neuroscience · 2022Article
- The importance of basal-temporal white matter to pre- and post-surgical naming ability in temporal lobe epilepsy.NeuroImage. Clinical · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
As part of silent reading models, visual orthographic information is transduced into an auditory phonological code in a process of grapheme-to-phoneme conversion (GPC). This process is often identified with lateral temporal-parietal regions associated with auditory phoneme encoding. However, the role of articulatory phonemic representations and the precentral gyrus in GPC is ambiguous. Though the precentral gyrus is implicated in many functional MRI studies of reading, it is not clear if the time course of activity in this region is consistent with the precentral gyrus being involved in GPC. We recorded cortical electrophysiology during a bimodal match/mismatch task from eight patients with perisylvian subdural electrodes to examine the time course of neural activity during a task that necessitated GPC. Patients made a match/mismatch decision between a 3-letter string and the following auditory bi-phoneme. We characterized the distribution and timing of evoked broadband high gamma (70-170 Hz) as well as phase-locking between electrodes. The precentral gyrus emerged with a high concentration of broadband high gamma responses to visual and auditory language as well as mismatch effects. The pars opercularis, supramarginal gyrus, and superior temporal gyrus were also involved. The precentral gyrus showed strong phase-locking with the caudal fusiform gyrus during letter-string presentation and with surrounding perisylvian cortex during the bimodal visual-auditory comparison period. These findings hint at a role for precentral cortex in transducing visual into auditory codes during silent reading.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.