Evidence map›Paper›PMID 37215267›Full record

ArticleIndian journal of endocrinology and metabolism

Thyroid Autoimmunity and Subclinical Hypothyroidism in Prolactinoma: A Case Control Study.

Bashir A Laway, Danendra Sahu, Moomin H Bhat, Mohammad S Baba, S Arun Viswanath, Raiz A Misgar, Arshad Iqbal Wani, Mir Iftikhar Bashir, Zaffar Amin Shah, Syed Mudassar

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Bashir A LawayDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Danendra SahuDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Moomin H BhatDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Mohammad S BabaDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
S Arun ViswanathDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Raiz A MisgarDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Arshad Iqbal WaniDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Mir Iftikhar BashirDepartment of Endocrinology, Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Zaffar Amin ShahDepartment of Immunology and Molecular Medicine, Srinagar, Jammu and Kashmir, India.
Syed MudassarDepartment of Biochemistry, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Sher-i-Kashmir Institute of Medical Sciences · INCluster University Srinagar · INUniversity of Kashmir · INShri Maharaja Hari Singh Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study was aimed at determining the frequency of thyroid autoimmunity and subclinical hypothyroidism in patients with hyperprolactinemia due to prolactinoma compared to well-matched healthy controls. Methods: This was a cross-sectional study wherein 78 treatment naïve prolactinoma patients and ninety-two healthy control subjects were recruited. Serum prolactin (PRL), thyroid-stimulating hormone (TSH), total thyroxine (T4), circulating anti-thyroid peroxidase (anti-TPO), and anti-thyroglobulin (anti-Tg) antibody levels were measured in all study subjects. Progression of the antibody-positive population to subclinical hypothyroidism was determined. Results: The median PRL level among patients was 166 ng/ml (IQR 85-467) compared to 11.4 ng/ml (IQR 8.5-15.9) in controls ( Conclusion: We did not find an increased prevalence of thyroid autoimmunity among untreated prolactinoma patients compared to healthy controls. At the same time, subclinical hypothyroidism was more common in thyroid antibody-positive patients with hyperprolactinemia than positive controls.

Indexed as

anti-TgAnti-TPOautoimmune thyroid diseasehyperprolactinemiaprolactinprolactinomasubclinical hypothyroidism

Identifiers

PMID37215267
PMCPMC10198196
OpenAlexW4322747563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.