Evidence map›Paper›PMID 37215071›Full record

ArticleBMJ medicine2023

Changes in the care of acute cerebrovascular and cardiovascular conditions during the first year of the covid-19 pandemic in 746 hospitals in the USA: retrospective analysis.

Raul G Nogueira, Katherine Etter, Thanh N Nguyen, Shelly Ikeme, Charlene Wong, Michael Frankel, Diogo C Haussen, Carlos Del Rio, Michael McDaniel, Rajesh Sachdeva and 9 more

Open access · goldAbstract read
In one paragraph

Article in BMJ medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Raul G NogueiraDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Katherine EtterGlobal Provider and Payer Value Demonstration, Health Economics and Market Access, Johnson & Johnson, Raynham, MA, USA.
Thanh N NguyenDepartment of Neurology, Boston University School of Medicine, Boston, MA, USA.ORCID 0000-0002-2810-1685
Shelly IkemeFranchise Health Economics and Market Access, Johnson & Johnson, New Brunswick, NJ, USA.
Charlene WongGlobal Provider and Payer Value Demonstration, Health Economics and Market Access, Johnson & Johnson, Raynham, MA, USA.
Michael FrankelDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Diogo C HaussenDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Carlos Del RioDepartment of Medicine, Grady Memorial Hospital, Atlanta, GA, USA.
Michael McDanielDepartment of Cardiology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA, USA.
Rajesh SachdevaDepartment of Cardiology, Veterans Affairs Medical Center, Atlanta, GA, USA.
Chandan M DevireddyDepartment of Cardiology, Emory University Hospital Midtown, Emory University School of Medicine, Atlanta, GA, USA.
Alhamza R Al-BayatiDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Mahmoud H MohammadenDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-7393-9989
Mohamed F DoheimDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Agostinho C PinheiroDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-2496-9479
Bernardo LiberatoDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Dinesh V JillellaDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Nirav R BhattDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Rahul KhannaMedical Device Epidemiology, Johnson and Johnson Medical Devices, New Brunswick, NJ, USA.
Grady Memorial Hospital · USUniversity of Pittsburgh · USJohnson & Johnson (United States) · USBoston University · USEmory University · USEmory University Hospital Midtown · USVeterans Health Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To measure the impact of the covid-19 pandemic on admissions to hospital and interventions for acute ischemic stroke and acute myocardial infarction. Design: A retrospective analysis. Setting: 746 qualifying hospitals in the USA from the Premier Healthcare Database. Participants: Patients aged 18 years and older who were admitted to hospital with a primary diagnosis of acute ischemic stroke or acute myocardial infarction between 1 March 2019 and 28 February 2021. Main outcome measures: Relative changes in volumes were assessed for acute ischemic stroke and acute myocardial infarction hospital admissions as well as intravenous thrombolysis, mechanical thrombectomy, and percutaneous coronary intervention (overall and for acute myocardial infarction only) across the first year of the pandemic versus the prior year. Mortality in hospital and length of stay in hospital were also compared across the first year of the pandemic versus the corresponding period the year prior. These metrics were explored across the different pandemic waves. Results: Among 746 qualifying hospitals, admissions to hospital were significantly reduced after the covid-19 pandemic compared with before the pandemic for acute ischemic stroke (-13.59% (95% confidence interval-13.77% to -13.41%) and acute myocardial infarction (-17.20% (-17.39% to -17.01%)), as well as intravenous thrombolysis (-9.47% (-9.99% to -9.02%)), any percutaneous coronary intervention (-17.89% (-18.06% to -17.71%)), and percutaneous coronary intervention for acute myocardial infarction (-14.36% (-14.59% to -14.12%)). During the first year of the pandemic versus the previous year, the odds of mortality in hospital for acute ischemic stroke were 9.00% higher (3.51% Conclusions: We observed substantial decreases in admissions to hospital with acute ischemic stroke and acute myocardial infarction, but an increase in mortality in hospital throughout the first year of the pandemic. Public health interventions are needed to prevent these reductions in future pandemics.

Indexed as

COVID-19Myocardial infarctionStroke

Identifiers

PMID37215071
PMCPMC10186086
OpenAlexW4376956881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.