ArticleFunctional ecology2023
Helminth-associated changes in host immune phenotype connect top-down and bottom-up interactions during co-infection.
Article in Functional ecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- A systematic review of the diversity and virulence correlates of metastrongyle lungworms in marine mammals.Parasitology · 2023Pooled it
- In vivo reduction of Treg expansion in rodent helminth-malaria coinfection.Parasites & vectors · 2026Article
- Counterproductive: coinfection of a water flea by a fungus and a microsporidium reduces the reproductive outputs of all parties.Scientific reports · 2026Article
- Coinfection with malaria alters the fecundity and within-host persistence of an intestinal nematode.PLoS neglected tropical diseases · 2026Article
- A cross-sectional study reveals complex associations between gastrointestinal parasite composition and faecal immune and inflammatory biomarkers in wildlife and livestock in Kenya.Frontiers in immunology · 2026Article
- Resources Modulate Developmental Shifts but Not Infection Tolerance Upon Co-Infection in an Insect System.Molecular ecology · 2025Article
- Resources modulate developmental shifts but not infection tolerance upon coinfection in an insect system.bioRxiv : the preprint server for biology · 2024Article
- Article
- Helminth-associated changes in host immune phenotype connect top-down and bottom-up interactions during co-infection.Functional ecology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
1. Within-host parasite interactions can be mediated by the host and changes in host phenotypes often serve as indicators of the presence or intensity of parasite interactions. 2. Parasites like helminths induce a range of physiological, morphological, and immunological changes in hosts that can drive bottom-up (resource-mediated) or top-down (immune-mediated) interactions with co-infecting parasites. Although top-down and bottom-up interactions are typically studied in isolation, the diverse phenotypic changes induced by parasite infection may serve as a useful tool for understanding if, and when, these processes act in concert. 3. Using an anthelmintic treatment study of African buffalo (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.