Evidence map›Paper›PMID 37214709›Full record

ArticleACS omega2023

Appraisal of Pancreatic Lipase Inhibitory Potential of

Srinivasa R Vulichi, Ashish Runthala, Siva K Rachamreddy, Radhika S P Yaramanedi, Partha Sarathi Sahoo, Prasad V L S Burra, Nameet Kaur, Sudheer Akkiraju, Somasekhar Reddy Kanala, Appa Rao Chippada and 1 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Srinivasa R VulichiS V University College of Pharmaceutical Sciences, S V University, Tirupati, Andhra Pradesh 517502, India.ORCID https://orcid.org/0000-0002-1873-1288
Ashish RunthalaDepartment of Biotechnology, Koneru Lakshmaiah Education Foundation, Vijayawada, Andhra Pradesh 522503, India.ORCID https://orcid.org/0000-0002-1835-2755
Siva K RachamreddyS V University College of Pharmaceutical Sciences, S V University, Tirupati, Andhra Pradesh 517502, India.
Radhika S P YaramanediS V University College of Pharmaceutical Sciences, S V University, Tirupati, Andhra Pradesh 517502, India.
Partha Sarathi SahooDepartment of Biotechnology, Koneru Lakshmaiah Education Foundation, Vijayawada, Andhra Pradesh 522503, India.
Prasad V L S BurraDepartment of Biotechnology, Koneru Lakshmaiah Education Foundation, Vijayawada, Andhra Pradesh 522503, India.
Nameet KaurOperon Technologies, New Delhi 110058, India.
Sudheer AkkirajuDepartment of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)- Autonomous, Anantapur, Andhra Pradesh 515721, India.
Somasekhar Reddy KanalaDepartment of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)- Autonomous, Anantapur, Andhra Pradesh 515721, India.
Appa Rao ChippadaS V University College of Pharmaceutical Sciences, S V University, Tirupati, Andhra Pradesh 517502, India.
Sistla Durga Srinivasa MurthyDepartment of Biochemistry, S V University, Tirupati, Andhra Pradesh 517502, India.
Sri Venkateswara University · INKoneru Lakshmaiah Education Foundation · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic lipase is one of the crucial lipolytic enzymes of the gut that actively facilitates the digestion and absorption of the dietary triglycerides and cholesteryl esters. Although it has been deemed as one of the most reliable targets for the treatment of obesity and/or dyslipidemia, to date, orlistat is the only known FDA-approved, effective, oral pancreatic lipase inhibitor available for clinical use apart from the centrally acting antiobesity agents. However, it is known to be associated with adverse gastrointestinal and renal complications. In this study, we attempted to assess the antioxidant and porcine pancreatic lipase inhibitory potentials of

Identifiers

PMID37214709
PMCPMC10193397
OpenAlexW4377565388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.