Evidence map›Paper›PMID 37214682›Full record

ArticleACS omega2023

Quinolone-3-amidoalkanol: A New Class of Potent and Broad-Spectrum Antimicrobial Agent.

Phelelisiwe S Dube, Klaudia T Angula, Lesetja J Legoabe, Audrey Jordaan, Jan M Boitz Zarella, Digby F Warner, J Stone Doggett, Richard M Beteck

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Phelelisiwe S DubeCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.
Klaudia T AngulaCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.
Lesetja J LegoabeCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.
Audrey JordaanSAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town Observatory, Cape Town 7925, South Africa.
Jan M Boitz ZarellaDivision of Infectious Diseases, VA Portland Healthcare System, Portland, Oregon 97239, United States.
Digby F WarnerSAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town Observatory, Cape Town 7925, South Africa.ORCID https://orcid.org/0000-0002-4146-0930
J Stone DoggettDivision of Infectious Diseases, VA Portland Healthcare System, Portland, Oregon 97239, United States.ORCID https://orcid.org/0000-0002-6098-1520
Richard M BeteckCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom 2520, South Africa.ORCID https://orcid.org/0000-0002-6282-043X
North-West University · ZASouth African Medical Research Council · ZAVA Portland Health Care System · US

Funding

BLRD VA I01 BX004522
6 · The paper itself

Abstract

Herein, we describe 39 novel quinolone compounds bearing a hydrophilic amine chain and varied substituted benzyloxy units. These compounds demonstrate broad-spectrum activities against acid-fast bacterium, Gram-positive and -negative bacteria, fungi, and leishmania parasite. Compound

Identifiers

PMID37214682
PMCPMC10193574
OpenAlexW4377565460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.