Evidence map›Paper›PMID 37214311›Full record

ArticleMolecular therapy. Methods & clinical development2023

Modeling

Almira Kurbegovic, Rey Christian Pacis, Marie Trudel

Expression of concernOpen access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. In vivo base editing reduces liver cysts in autosomal dominant polycystic kidney disease.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  6. Article
  7. Article
  8. Prospects for gene therapy in polycystic kidney disease.Current opinion in nephrology and hypertension · 2025
    Review
  9. Gene therapy in polycystic kidney disease: A promising future.Journal of translational internal medicine · 2024
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Almira KurbegovicInstitut de Recherches Cliniques de Montréal, Faculté de, Médecine, Montreal, QC, Canada.
Rey Christian PacisInstitut de Recherches Cliniques de Montréal, Faculté de, Médecine, Montreal, QC, Canada.
Marie TrudelInstitut de Recherches Cliniques de Montréal, Faculté de, Médecine, Montreal, QC, Canada.
Montreal Clinical Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) causes renal cysts and leads to end-stage renal disease in midlife due mainly to

Indexed as

Pc1Pkd1 gene therapyPkd1 locus/minigenePkd1 RNAscopePKD mouse modelsPKD transcriptional regulationpolycystic kidney diseasepolycystinsmall SB renal cassette

Identifiers

PMID37214311
PMCPMC10199405
OpenAlexW4362580464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.