Evidence map›Paper›PMID 37214207›Full record

ArticleJournal of immunotherapy and precision oncology2023

COVID-19 Outcomes in Patients with Cancer Receiving Immune Checkpoint Inhibitors: A Systematic Review.

Juan I Ruiz, Maria A Lopez-Olivo, Yimin Geng, Maria E Suarez-Almazor

Open access · goldAbstract read
In one paragraph

Article in Journal of immunotherapy and precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Juan I RuizHealth Services Research Department, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.ORCID https://orcid.org/0000-0002-0885-134X
Maria A Lopez-OlivoHealth Services Research Department, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
Yimin GengResearch Medical Library, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
Maria E Suarez-AlmazorHealth Services Research Department, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.ORCID https://orcid.org/0000-0001-5381-5797
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Improving decision-making in patients with resectable melanoma and pre-existing autoimmune disease considering immune checkpoint inhibitionK08CA237619 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LOPEZ-OLIVO, MARIA DE LOS ANGELES · 2020 to 2024
$938k
NCI NIH HHS K08 CA237619NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Introduction: Immune checkpoint inhibitors (ICIs) can cause inflammatory and immune-related adverse events (irAEs) that might worsen the course of COVID-19. We conducted a systematic review (PROSPERO ID: CRD42022307545) to evaluate the clinical course and complications of COVID-19 in patients with cancer receiving ICI. Methods: We searched Medline and Embase through January 5, 2022. We included studies evaluating patients with cancer who received ICI and developed COVID-19. Outcomes included mortality, severe COVID-19, intensive care unit (ICU) and hospital admissions, irAEs, and serious adverse events. We pooled data with random effects meta-analysis. Results: Twenty-five studies met study eligibility ( Conclusion: Although current evidence is limited, COVID-19 clinical outcomes of patients with cancer receiving ICI therapy appear to be similar to those not receiving oncologic treatment or other cancer therapies.

Indexed as

COVID-19immune checkpoint inhibitorsimmune-related adverse eventsimmunotherapySARS-CoV-2

Identifiers

PMID37214207
PMCPMC10195019
OpenAlexW4321491150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.