Evidence map›Paper›PMID 37214015›Full record

ReviewCureus2023

Knee Loading With Blood Flow Restriction Can Enhance Recovery After Total Knee Arthroplasty.

Clément De Renty, Florian Forelli, Jean Mazeas, Georgios Kakavas, Timothy E Hewett, Vasileios Korakakis

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07141316 (Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07141316 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty: Randomized Controlled Trial

TypeinterventionalSponsorUniversity of PaviaRan2025 to 2026Enrolled60ConditionsOsteo Arthritis KneeArmsBlood flow restriction combined with electrostimulation.
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 6 countries.

Clément De RentyMedicine and Research for High-Performance Sports, Centre Départemental de Formation en Activités Sportives (CDFAS), Eaubonne, FRA.
Florian ForelliResearch and Development, Société Française des Masseurs Kinésithérapeutes du Sport (SFMKS) Lab, Pierrefitte sur Seine, FRA.
Jean MazeasOrthopedic Surgery, Clinic of Domont, Domont, FRA.
Georgios KakavasSpine and Sports Laboratory, Fysiotek, Athens, GRC.
Timothy E HewettOrthopedic Surgery, Marshall University, Huttington, USA.
Vasileios KorakakisPhysiotherapy, King's College, London, GBR.
King's College - North Carolina · USDomus Medica · BEMarshall University · USSociété Française de Médecine d'Urgence · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total knee arthroplasty (TKA) is one of the most performed operations in the world, especially in the elderly. Aging has a significant effect on joint cartilage, muscle strength, and muscle mass. Following a TKA, despite the significant reduction of symptoms and the improvement in mobility, muscle strength and muscle mass recovery remains a significant challenge. Restrictions that arise from the surgical procedure include joint loading, functional activities, and range of motion, along with limitations related to the age of the individual and their previous loading history, these are the significant restrictions, at least in the early stages of rehabilitation. Evidence indicates that blood flow restriction (BFR) training has significant potential to enhance recovery via implementation of low-load or low-intensity exercise. While respecting the indications and contraindications related to BFR application, the optimization of metabolic stress seems to offer a bridging therapy to heavy load while reducing pain and inflammation. Thus, the combination of BFR and low loads may improve muscular recovery (strength and mass), and aerobic training protocols appear to show significant enhancement of multiple cardiopulmonary parameters. Mounting evidence, direct and indirect, indicate that BFR training may have the potential to benefit the pre-operative and post-operative TKA rehabilitation phases and enhance functional recovery and physical abilities in the elderly.

Indexed as

blood flow restrictionbridging therapyelderlylow loadtotal knee arthroplasty

Identifiers

PMID37214015
PMCPMC10199744
OpenAlexW4366590897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.